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成人前列腺横纹肌肉瘤:一份具有完整分子图谱的病例报告

Rhabdomyosarcoma of the Adult Prostate: A Case Report With Complete Molecular Profile.

作者信息

Olivas Andrea D, Antic Tatjana

机构信息

University of Chicago, Chicago, IL, USA.

出版信息

Int J Surg Pathol. 2020 Feb;28(1):92-98. doi: 10.1177/1066896919867763. Epub 2019 Aug 13.

Abstract

Primary rhabdomyosarcoma of the adult prostate is rare and associated with an aggressive clinical course. Given the limited number of cases reported about the prostate, little is known about the impact of molecular mutations on tumor biology and prognosis in adults. In this article, we present a case of primary embryonal rhabdomyosarcoma of the adult prostate with a complete molecular mutational profile of the tumor.

摘要

成人前列腺原发性横纹肌肉瘤罕见,且临床病程侵袭性强。鉴于报道的前列腺相关病例数量有限,关于分子突变对成人肿瘤生物学及预后的影响知之甚少。在本文中,我们报告一例成人前列腺原发性胚胎性横纹肌肉瘤病例,并给出该肿瘤完整的分子突变谱。

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