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成人前列腺横纹肌肉瘤:一份具有完整分子图谱的病例报告

Rhabdomyosarcoma of the Adult Prostate: A Case Report With Complete Molecular Profile.

作者信息

Olivas Andrea D, Antic Tatjana

机构信息

University of Chicago, Chicago, IL, USA.

出版信息

Int J Surg Pathol. 2020 Feb;28(1):92-98. doi: 10.1177/1066896919867763. Epub 2019 Aug 13.

DOI:10.1177/1066896919867763
PMID:31409181
Abstract

Primary rhabdomyosarcoma of the adult prostate is rare and associated with an aggressive clinical course. Given the limited number of cases reported about the prostate, little is known about the impact of molecular mutations on tumor biology and prognosis in adults. In this article, we present a case of primary embryonal rhabdomyosarcoma of the adult prostate with a complete molecular mutational profile of the tumor.

摘要

成人前列腺原发性横纹肌肉瘤罕见,且临床病程侵袭性强。鉴于报道的前列腺相关病例数量有限,关于分子突变对成人肿瘤生物学及预后的影响知之甚少。在本文中,我们报告一例成人前列腺原发性胚胎性横纹肌肉瘤病例,并给出该肿瘤完整的分子突变谱。

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1
Rhabdomyosarcoma of the Adult Prostate: A Case Report With Complete Molecular Profile.成人前列腺横纹肌肉瘤:一份具有完整分子图谱的病例报告
Int J Surg Pathol. 2020 Feb;28(1):92-98. doi: 10.1177/1066896919867763. Epub 2019 Aug 13.
2
[Prostatic rhabdomyosarcoma in adults].[成人前列腺横纹肌肉瘤]
Arch Esp Urol. 1998 Nov;51(9):883-8.
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Genomic profiling of pleomorphic rhabdomyosarcoma reveals a genomic signature distinct from that of embryonal rhabdomyosarcoma.多形性横纹肌肉瘤的基因组分析显示出与胚胎性横纹肌肉瘤不同的基因组特征。
Genes Chromosomes Cancer. 2024 May;63(5):e23238. doi: 10.1002/gcc.23238.
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Fine needle aspiration of prostatic rhabdomyosarcoma. A case report demonstrating the value of DNA ploidy.前列腺横纹肌肉瘤的细针穿刺活检。一例显示DNA倍体价值的病例报告。
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Prostatic embryonal rhabdomyosarcoma in adults. A clinicopathologic review.成人前列腺胚胎性横纹肌肉瘤。临床病理回顾。
Cancer. 1992 Feb 1;69(3):755-62. doi: 10.1002/1097-0142(19920201)69:3<755::aid-cncr2820690324>3.0.co;2-y.
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Rhabdomyosarcoma: How Advanced Molecular Methods Are Shaping the Diagnostic and Therapeutic Paradigm.横纹肌肉瘤:先进分子方法如何塑造诊断和治疗模式
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Beyond "Triton": Malignant Peripheral Nerve Sheath Tumors With Complete Heterologous Rhabdomyoblastic Differentiation Mimicking Spindle Cell Rhabdomyosarcoma.超越“海神”:具有完全异源横纹肌母细胞分化的恶性外周神经鞘瘤,模仿梭形细胞横纹肌肉瘤。
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Spindle cell rhabdomyosarcoma of the prostate.前列腺梭形细胞横纹肌肉瘤。
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Three pediatric patients with extension of prostatic embryonal rhabdomyosarcoma anterior to the bladder into the space of Retzius.三名患有前列腺胚胎性横纹肌肉瘤的儿科患者,肿瘤延伸至膀胱前方进入Retzius间隙。
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Embryonal rhabdomyosarcoma of the prostate.前列腺胚胎性横纹肌肉瘤。
Int J Clin Oncol. 2010 Feb;15(1):93-6. doi: 10.1007/s10147-009-0004-6. Epub 2010 Jan 20.

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Embryonal rhabdomyosarcoma of prostate combined with prostatic abscess in an adult patient: a case report and literature review.成年患者前列腺胚胎性横纹肌肉瘤合并前列腺脓肿:一例报告及文献复习
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Hyperfibrinolysis during the treatment of rhabdomyosarcoma.
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Res Pract Thromb Haemost. 2024 May 31;8(4):102467. doi: 10.1016/j.rpth.2024.102467. eCollection 2024 May.
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Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient: a case report and review of the literature.成人前列腺梭形细胞胚胎性横纹肌肉瘤:病例报告及文献复习。
J Int Med Res. 2024 Mar;52(3):3000605241234755. doi: 10.1177/03000605241234755.
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