Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Department of Urology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
J Int Med Res. 2024 Mar;52(3):3000605241234755. doi: 10.1177/03000605241234755.
Rhabdomyosarcoma of the prostate is a rare mesenchymal tumor that originates from undifferentiated mesenchymal cells. Spindle cell rhabdomyosarcoma is a variant of embryonal rhabdomyosarcoma. The vast majority of these two pathological types occur in children, with only a few adult cases reported to date, and both are associated with poor clinical outcomes. We herein report a case involving a man in his early 40s with spindle cell embryonal rhabdomyosarcoma of the prostate. His chief complaint was difficult urination. The diagnosis was confirmed by puncture biopsy of the prostate, and pelvic lymph node metastasis was already present at the time of diagnosis. The patient underwent three courses of chemotherapy. However, his response to the treatment was very poor, and he died of the disease 4 months after diagnosis.
前列腺横纹肌肉瘤是一种罕见的间叶性肿瘤，来源于未分化的间叶细胞。梭形细胞横纹肌肉瘤是胚胎性横纹肌肉瘤的一种变体。这两种病理类型绝大多数发生在儿童中，迄今为止仅报告了少数成人病例，且两者的临床结局均较差。本文报告了一例 40 岁出头的男性前列腺梭形细胞胚胎性横纹肌肉瘤患者。他的主要症状是排尿困难。通过前列腺穿刺活检确诊，诊断时已存在盆腔淋巴结转移。患者接受了 3 个疗程的化疗。然而，他对治疗的反应非常差，在确诊后 4 个月因疾病去世。
