The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Denmark.
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Denmark.
Scand J Public Health. 2020 Jul;48(5):567-576. doi: 10.1177/1403494819868592. Epub 2019 Aug 14.
Little is known about the prevalence and characteristics of functional somatic syndromes (FSS) such as irritable bowel syndrome (IBS), fibromyalgia (FM), chronic fatigue syndrome (CFS), whiplash associated disorders (WAD), multiple chemical sensitivity (MCS), and bodily distress syndrome (BDS) in the general population when they are investigated simultaneously. : This cross-sectional study is based on the Danish Study of Functional Disorders (DanFunD) cohort consisting of 9656 adults from the general population. FSS and BDS were identified by questionnaires and characterized by age, sex, vocational training, physical health and comorbidity with physical and psychiatric disease. : In total, 16.3% (95% CI: 15.6-17.1) of the participants fulfilled the criteria for at least one FSS, ranging from 1.7% for WAD to 8.6% for CFS, and 16.1% (95% CI: 15.4-16.9) fulfilled the criteria for BDS. Cases had a high risk of poor self-perceived health, limitations in daily activities, and a high psychiatric comorbidity, all increasing with the number of syndromes in each individual. However, the associations differed across the various FSS. Mutual overlaps of IBS, FM and CFS were greater than could be expected by chance.
当同时调查一般人群中的功能性躯体综合征（FSS），如肠易激综合征（IBS）、纤维肌痛（FM）、慢性疲劳综合征（CFS）、挥鞭样损伤相关障碍（WAD）、多种化学物质敏感性（MCS）和躯体不适综合征（BDS）时，人们对其患病率和特征知之甚少。本横断面研究基于丹麦功能性疾病研究（DanFunD）队列，该队列包括来自一般人群的 9656 名成年人。通过问卷确定 FSS 和 BDS，并通过年龄、性别、职业培训、身体健康状况以及与身体和精神疾病的共病情况进行特征描述。共有 16.3%（95%可信区间：15.6-17.1）的参与者符合至少一种 FSS 的标准，范围从 1.7%的 WAD 到 8.6%的 CFS，16.1%（95%可信区间：15.4-16.9）符合 BDS 的标准。病例组自我感知健康状况较差、日常活动受限和精神共病率高的风险较高，所有这些都随着个体中综合征的数量增加而增加。然而，各种 FSS 的关联不同。IBS、FM 和 CFS 之间的相互重叠大于随机预期。
