Baran D T, Kelly A M, Karellas A, Gionet M, Price M, Leahey D, Steuterman S, McSherry B, Roche J
Department of Orthopedics, University of Massachusetts Medical Center, Worcester 01655.
Calcif Tissue Int. 1988 Sep;43(3):138-42. doi: 10.1007/BF02571310.
Bone ultrasound attenuation of the calcaneus, and vertebral and femoral bone density measured by dual photon absorption were determined in 22 women with osteoporosis, 10 women with hip fractures, and 29 normal, age-matched controls to determine the utility of the ultrasound technique as an indicator of axial osteopenia. Vertebral and femoral neck density and bone ultrasound attenuation were significantly decreased (P less than 0.01) in the women with osteoporosis and those with hip fractures. The sensitivity and specificity of bone ultrasound attenuation was 80% at a value of 50 dB/MHz. At 90% specificity the sensitivity of bone ultrasound attenuation was 65%. The results of this pilot study suggest that ultrasound attenuation, a safe, simple, and radiation-free procedure, may be utilized as an indicator of decreased axial bone mass.
对22名骨质疏松症女性、10名髋部骨折女性以及29名年龄匹配的正常对照者，测定了跟骨的骨超声衰减以及通过双能光子吸收法测量的椎骨和股骨骨密度，以确定超声技术作为轴向骨质减少指标的实用性。骨质疏松症女性和髋部骨折女性的椎骨和股骨颈密度以及骨超声衰减均显著降低（P<0.01）。骨超声衰减值为50dB/MHz时，其敏感性和特异性为80%。特异性为90%时，骨超声衰减的敏感性为65%。这项初步研究结果表明，超声衰减作为一种安全、简单且无辐射的检查方法，可用于作为轴向骨量减少的指标。
