André M P, Craven J D, Greenfield M A, Stern R
Med Phys. 1980 Jul-Aug;7(4):324-30. doi: 10.1118/1.594713.
A pulse-echo technique for measuring the velocity of ultrasound in the cortex of the femur in vivo is presented. The average result for 27 asymptomatic volunteers is 3250 +/- 190 m/s. The results show no significant differences between proximal and distal femoral sites, right and left femora, males and females. There is also no significant difference between the velocity of sound in the femur and in the radius in normal volunteers. The reproducibility of the time of flight measurement for three volunteers is found to be about 2%, and the total uncertainty of the femoral velocity of ultrasound measurement is determined to be 4% for proximal sites and 7% for distal sites. As the femur is a load-bearing bone, the site of frequent fracture both in the elderly and in the osteoporotic, the measurement of the velocity of sound at this new site may be of great value in investigating these conditions and may ultimately be helpful in assessing "quality" of the femoral cortex in those patients undergoing total hip or knee replacement.
本文介绍了一种用于在体内测量股骨皮质中超声速度的脉冲回波技术。27名无症状志愿者的平均结果为3250 +/- 190米/秒。结果表明，股骨近端和远端部位、右股骨和左股骨、男性和女性之间无显著差异。正常志愿者的股骨和桡骨中的声速也无显著差异。发现三名志愿者飞行时间测量的可重复性约为2%，超声测量股骨速度的总不确定度对于近端部位确定为4%，对于远端部位为7%。由于股骨是一种承重骨，在老年人和骨质疏松症患者中都是骨折频发部位，在这个新部位测量声速对于研究这些病症可能具有重要价值，并且最终可能有助于评估接受全髋关节或膝关节置换手术患者的股骨皮质“质量”。
