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一名患有室中隔梗阻性肥厚型心肌病合并心尖部室壁瘤患者的室性心动过速与心力衰竭:病例报告

Ventricular tachycardia and heart failure in a patient of mid-ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report.

作者信息

Zhang Xin, Liu Xingbin

机构信息

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

出版信息

Exp Ther Med. 2019 Sep;18(3):2238-2242. doi: 10.3892/etm.2019.7796. Epub 2019 Jul 19.

Abstract

Mid-ventricular obstructive hypertrophic cardiomyopathy (MVOHC) with apical aneurysm is a rare type of cardiomyopathy. It is associated with an elevated risk of ventricular arrhythmias, thromboembolism, heart failure and sudden cardiac death. The present case study reports on a patient with MVOHC and apical aneurysm who developed ventricular arrhythmias and heart failure. The patient received an implantable cardioverter defibrillator for prevention of fatal arrhythmias. Ventricular tachycardia was terminated by increased doses of amiodarone and β-blocker. Transthoracic echocardiography indicated a mid-ventricular gradient of 64 mmHg. The patient refused surgical treatment and opted for alcohol septal ablation (ASA). At the 6-month follow-up, a rebound of the gradient following ASA was observed on echocardiography. In the present study, timely recognition of MVOHC with apical aneurysm led to prompt defibrillator implantation for prophylaxis regarding further malignant arrhythmias. Surgical management should be considered in symptomatic patients with MVOHC and apical aneurysm.

摘要

伴有心尖部室壁瘤的心室中部梗阻性肥厚型心肌病(MVOHC)是一种罕见的心肌病类型。它与室性心律失常、血栓栓塞、心力衰竭和心源性猝死风险升高相关。本病例研究报告了一名患有MVOHC和心尖部室壁瘤且发生室性心律失常和心力衰竭的患者。该患者接受了植入式心脏复律除颤器以预防致命性心律失常。通过增加胺碘酮和β受体阻滞剂剂量终止了室性心动过速。经胸超声心动图显示心室中部压力阶差为64 mmHg。患者拒绝手术治疗而选择了酒精室间隔消融术(ASA)。在6个月随访时,超声心动图观察到ASA后压力阶差出现反弹。在本研究中,及时识别伴有心尖部室壁瘤的MVOHC促使迅速植入除颤器以预防进一步的恶性心律失常。对于有症状的MVOHC和心尖部室壁瘤患者应考虑手术治疗。

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本文引用的文献

1
Early Outcomes of Repair of Left Ventricular Apical Aneurysms in Patients With Hypertrophic Cardiomyopathy.
Circulation. 2017 Nov 14;136(20):1979-1981. doi: 10.1161/CIRCULATIONAHA.117.030593.
4
Hypertrophic obstructive cardiomyopathy.肥厚型梗阻性心肌病。
Lancet. 2017 Mar 25;389(10075):1253-1267. doi: 10.1016/S0140-6736(16)31321-6. Epub 2016 Nov 30.

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