Saleem Maryam, Iftikhar Hassaan
Internal Medicine, Waterbury Hospital, Waterbury, USA.
Internal Medicine, St. Francis Medical Center, Seton Hall University, Trenton, USA.
Cureus. 2019 Jun 6;11(6):e4848. doi: 10.7759/cureus.4848.
Linear immunoglobulin A (IgA) bullous dermatosis, also known as linear IgA disease, is a rare disorder with an incidence of about 0.5 to 2.3 cases per million individuals per year. In most of the cases, the cause is unknown; however, 50% of the cases are drug-induced. The disease has bimodal age predilection and occurs in children up to the age of 10 years and in adults usually after the age of 60 years. Common drugs that have been known to cause this disease include vancomycin, lithium, amiodarone, captopril, and some of the nonsteroidal anti-inflammatory agents. We report a case of linear IgA disease secondary to vancomycin.
线状免疫球蛋白A（IgA）大疱性皮肤病，也称为线状IgA病，是一种罕见疾病，每年每百万人口中的发病率约为0.5至2.3例。在大多数病例中，病因不明；然而，50%的病例是药物诱发的。该疾病有双峰年龄偏好，发生在10岁以下的儿童以及通常60岁以上的成年人中。已知可导致这种疾病的常见药物包括万古霉素、锂盐、胺碘酮、卡托普利以及一些非甾体抗炎药。我们报告一例由万古霉素引起的线状IgA病病例。
