Vermeylen D, Godart S, Moretto M, Janssen F, Bouton J M
Paediatric Department, Free University of Brussels, Belgium.
Eur J Pediatr. 1988 Aug;147(6):649-52. doi: 10.1007/BF00442484.
A patient with congenital chloride diarrhoea (CCD) is reported. The diagnosis on the 5th day of life was based on the watery stools with characteristic ionic composition. The neonate presented with abdominal distension necessitating laparotomy on day 1, followed by transverse colostomy on day 3, owing to persistent abdominal swelling. Total parenteral nutrition (from 1 to 3 months) followed by an enteral semi-elemental diet (from 3 to 5 months) was required to reduce the quantity of stools and to obtain a satisfactory nutritional state. The colostomy was closed at 16 months. Growth, psychomotor development and renal function are normal at 6 years. Criteria for therapeutic evaluation are discussed.
报道了1例先天性氯腹泻（CCD）患者。出生第5天的诊断依据是具有特征性离子组成的水样便。该新生儿出生第1天因腹胀行剖腹手术，第3天因持续性腹部肿胀行横结肠造口术。为减少粪便量并达到满意的营养状态，需要先进行全胃肠外营养（1至3个月），随后给予肠内半要素饮食（3至5个月）。结肠造口术在16个月时关闭。6岁时生长、精神运动发育和肾功能均正常。讨论了治疗评估标准。
