• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

坦桑尼亚达累斯萨拉姆西北部地区社区药店中安定的非法配药行为:以模拟客户为方法。

Unlawful dispensing practice of diazepam: a simulated client approach in community pharmacies in the north-west of Dar-es-Salaam region, Tanzania.

机构信息

Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania.

School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania.

出版信息

BMC Health Serv Res. 2019 Aug 14;19(1):571. doi: 10.1186/s12913-019-4421-6.

DOI:10.1186/s12913-019-4421-6
PMID:31412944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6694629/
Abstract

BACKGROUND

The use of psychotropic substances is controlled in most parts of the world due to their potential of abuse and addiction. Diazepam is one of the psychotropic substances which can be dispensed in community pharmacies in Tanzania. As per good dispensing practices and pharmacy laws, diazepam in the community pharmacies should strictly be stored in a controlled box and dispensed only by prescription. However, to our understanding little had been reported on availability and dispensing practices of diazepam in Tanzania.

METHODS

A descriptive cross-sectional study which involved 178 randomly selected registered community pharmacies in Kinondoni district was conducted from January to March 2018. Simulated client approach was used to assess the availability and dispensers practice about dispensing of diazepam. Location of pharmacies was categorized as being at the centre or periphery of the Kinondoni district. Chi-squared test was used for the analysis of categorical data using SPSS version 23. The p-value of < 0.05 was considered significant.

RESULT

The total of 178 community pharmacies were visited, the majority of the dispensers (89.1%) encountered were female. Most (69.1%) of the studied pharmacies were located at the centre of Kinondoni district. Diazepam was available in 91% of community pharmacies and 70% of dispensers issued diazepam without prescription.

CONCLUSION

Diazepam was available in most of the community pharmacies in Kinondoni district, and the majority of the dispensers dispensed diazepam without prescription. This calls for the regulatory authorities to be more vigilant on the availability of diazepam and enhance the provision of ethical pharmacy practice in the community pharmacies.

摘要

背景

由于潜在的滥用和成瘾风险,世界上大多数地区都对精神药物的使用进行了管控。地西泮是一种精神药物,在坦桑尼亚的社区药房可以凭处方配给。根据良好的配药实践和药房法规,社区药房中的地西泮应严格存放在受控药盒中,并凭处方配给。然而,据我们了解,关于坦桑尼亚地西泮的供应和配药情况,相关报道很少。

方法

这是一项描述性的横断面研究,于 2018 年 1 月至 3 月期间在金多尼区随机选择了 178 家注册社区药房进行。采用模拟患者的方法评估地西泮的供应情况和配药师的配药实践。将药房的位置分为金多尼区中心和外围。使用 SPSS 版本 23 的卡方检验对分类数据进行分析。p 值<0.05 被认为具有统计学意义。

结果

共访问了 178 家社区药房,遇到的配药员中大多数(89.1%)为女性。在所研究的药房中,大多数(69.1%)位于金多尼区中心。地西泮在 91%的社区药房中均可获得,70%的配药员在没有处方的情况下配发了地西泮。

结论

地西泮在金多尼区的大多数社区药房中都有供应,而且大多数配药员在没有处方的情况下配发了地西泮。这呼吁监管机构更加警惕地西泮的供应情况,并加强社区药房的伦理药房实践的提供。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0b/6694629/5387d68dbd34/12913_2019_4421_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0b/6694629/5387d68dbd34/12913_2019_4421_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0b/6694629/5387d68dbd34/12913_2019_4421_Fig1_HTML.jpg

相似文献

1
Unlawful dispensing practice of diazepam: a simulated client approach in community pharmacies in the north-west of Dar-es-Salaam region, Tanzania.坦桑尼亚达累斯萨拉姆西北部地区社区药店中安定的非法配药行为:以模拟客户为方法。
BMC Health Serv Res. 2019 Aug 14;19(1):571. doi: 10.1186/s12913-019-4421-6.
2
Prescription and non-prescription antibiotic dispensing practices in part I and part II pharmacies in Moshi Municipality, Kilimanjaro Region in Tanzania: A simulated clients approach.坦桑尼亚乞力马扎罗地区莫希市第一类和第二类药店的处方和非处方抗生素配药做法:以模拟客户为方法。
PLoS One. 2018 Nov 21;13(11):e0207465. doi: 10.1371/journal.pone.0207465. eCollection 2018.
3
Antibiotic dispensing practice in community pharmacies: A simulated client study.社区药店的抗生素配药实践:一项模拟患者研究。
Res Social Adm Pharm. 2019 May;15(5):584-590. doi: 10.1016/j.sapharm.2018.07.019. Epub 2018 Jul 29.
4
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania.在坦桑尼亚,基于磺胺类药物的抗疟药物被限制用于孕妇间歇性预防治疗疟疾已经有十年了。
Malar J. 2018 Nov 6;17(1):409. doi: 10.1186/s12936-018-2565-1.
5
A cross-sectional national survey of community pharmacy staff: Knowledge and antibiotic provision.横断面全国社区药房员工调查:知识与抗生素供应
PLoS One. 2019 Apr 25;14(4):e0215484. doi: 10.1371/journal.pone.0215484. eCollection 2019.
6
Evaluation of medicines dispensing pattern of private pharmacies in Rajshahi, Bangladesh.孟加拉国拉杰沙希市私立药店药品配药模式评估。
BMC Health Serv Res. 2017 Feb 13;17(1):136. doi: 10.1186/s12913-017-2072-z.
7
Dispensing Practice of Prescribed Medicines in the Private Pharmacies in Urban Areas of Tanzania.坦桑尼亚城市地区私立药店的处方药配药实践
Indian J Pharm Sci. 2015 Sep-Oct;77(5):542-9. doi: 10.4103/0250-474x.169041.
8
Dispensing practices for anti-malarials in the La Nkwantanang-Madina municipality, Greater Accra, Ghana: a cross-sectional study.加纳大阿克拉地区拉恩昆坦南-马迪纳市的抗疟药物配给情况:一项横断面研究。
Malar J. 2019 Jul 30;18(1):260. doi: 10.1186/s12936-019-2897-5.
9
Drug dispensing practices at pharmacies in Bengaluru: A cross-sectional study.班加罗尔药房的药品配药实践:一项横断面研究。
Indian J Pharmacol. 2016 Jul-Aug;48(4):360-364. doi: 10.4103/0253-7613.186204.
10
Knowledge and dispensing practice of community pharmacists towards antipsychotic medicines in a Nigerian metropolitan city - a cross-sectional study.尼日利亚大都市社区药剂师对抗精神病药物的知识和配药实践-一项横断面研究。
BMC Health Serv Res. 2023 Dec 21;23(1):1450. doi: 10.1186/s12913-023-10480-0.

引用本文的文献

1
Determinants of Benzodiazepine-Dispensing Practice Among Community Pharmacy Dispensers in Dar es Salaam, Tanzania.坦桑尼亚达累斯萨拉姆社区药房药剂师苯二氮䓬类药物配药行为的影响因素
Adv Pharmacol Pharm Sci. 2025 Jun 3;2025:1404995. doi: 10.1155/adpp/1404995. eCollection 2025.
2
Availability of two essential medicines for mental health in Bangladesh, the Democratic Republic of Congo, Haiti, Nepal, Malawi, Senegal, and Tanzania: Evidence from nationally representative samples of 7958 health facilities.孟加拉国、刚果民主共和国、海地、尼泊尔、马拉维、塞内加尔和坦桑尼亚 7958 家卫生机构的全国代表性样本显示,这两个基本精神卫生药物在这些国家的供应情况。
J Glob Health. 2022 Aug 1;12:04063. doi: 10.7189/jogh.12.04063.

本文引用的文献

1
Irrational Use of Medicines-A Summary of Key Concepts.药品的不合理使用——关键概念总结
Pharmacy (Basel). 2016 Oct 28;4(4):35. doi: 10.3390/pharmacy4040035.
2
Sample Size Calculations for Population Size Estimation Studies Using Multiplier Methods With Respondent-Driven Sampling Surveys.使用乘数法和应答驱动抽样调查进行总体规模估计研究的样本量计算
JMIR Public Health Surveill. 2017 Sep 14;3(3):e59. doi: 10.2196/publichealth.7909.
3
Extent of dispensing prescription-only medications without a prescription in community drug retail outlets in Addis Ababa, Ethiopia: a simulated-patient study.
埃塞俄比亚亚的斯亚贝巴社区药店无处方配药的程度:一项模拟患者研究。
Drug Healthc Patient Saf. 2016 Jul 14;8:65-70. doi: 10.2147/DHPS.S106948. eCollection 2016.
4
Dispensing Practice of Prescribed Medicines in the Private Pharmacies in Urban Areas of Tanzania.坦桑尼亚城市地区私立药店的处方药配药实践
Indian J Pharm Sci. 2015 Sep-Oct;77(5):542-9. doi: 10.4103/0250-474x.169041.
5
Prescription Sedative Misuse and Abuse.处方镇静剂的误用与滥用。
Yale J Biol Med. 2015 Sep 3;88(3):247-56. eCollection 2015 Sep.
6
Classics in chemical neuroscience: diazepam (valium).经典神经化学:地西泮(安定)。
ACS Chem Neurosci. 2014 Apr 16;5(4):253-60. doi: 10.1021/cn5000056. Epub 2014 Feb 27.
7
Twenty-year trends in benzodiazepine dispensing in the Australian population.澳大利亚人群中苯二氮䓬类药物配药的 20 年趋势。
Intern Med J. 2014 Jan;44(1):57-64. doi: 10.1111/imj.12315.
8
Prevalence of benzodiazepines misuse in Ubon Ratchathani province Thailand.
J Med Assoc Thai. 2011 Jan;94(1):118-22.
9
Sample size calculation.样本量计算。
Int J Ayurveda Res. 2010 Jan;1(1):55-7. doi: 10.4103/0974-7788.59946.
10
A strategy for promoting improved pharmaceutical use: the International Network for Rational Use of Drugs.促进合理用药的一项策略:国际合理用药网络
Soc Sci Med. 1992 Dec;35(11):1329-41. doi: 10.1016/0277-9536(92)90037-q.