Aslam Itzaz, Iqbal Javed, Peerzada Sohaib, Afridi Muhammad S K, Ishtiaq Saiqa
Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
Punjab University College of Pharmacy, University of the Punjab, Allama Iqbal Campus, Lahore, 54000, Pakistan.
Microsc Res Tech. 2019 Nov;82(11):1891-1902. doi: 10.1002/jemt.23357. Epub 2019 Aug 15.
Herbal medicines frequently suffer with quality controversies because of similar species or varieties. This often leads to sophistication or admixture of the crude drug as they share various look alike physical features. Commercially, stalks of Caralluma edulis are commonly adulterated with other species because of their analogous morphology. In the present research, the microscopic standardization of the drug was performed by structural, histological, and anatomical features. Pharmacognostical characterization was carried out by physicochemical (moisture content, swelling index, pH value, ash values, and extractive values) and fluorescence analysis. The chemical characterization by UV-Visible, Fourier transform infrared spectroscopy, and high-performance liquid chromatography was also performed that disclosed the chief phytoconstituents of the herbal drug. The above mentioned constraints, being reported for the first time in C. edulis, are substantial in establishing the microscopic and pharmacopoeial standards for future identification and authentication.
由于存在相似的物种或变种,草药经常面临质量争议。这常常导致生药掺假或混杂,因为它们具有各种相似的外观物理特征。在商业上,可食牛角瓜的茎常因形态相似而被其他物种掺假。在本研究中,通过结构、组织学和解剖学特征对该药物进行了微观标准化。通过物理化学(水分含量、膨胀指数、pH值、灰分值和提取物值)和荧光分析进行了生药学特征鉴定。还进行了紫外可见光谱、傅里叶变换红外光谱和高效液相色谱的化学表征,揭示了该草药的主要植物成分。上述限制因素首次在可食牛角瓜中被报道,对于建立未来鉴定和认证的微观和药典标准具有重要意义。