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玻璃体内注射贝伐单抗治疗双侧念珠菌性脉络膜炎合并脉络膜新生血管。

Intravitreal Bevacizumab for Treatment of Bilateral Candida Chorioretinitis Complicated with Choroidal Neovascularization.

机构信息

Department of Ophthalmology, UZ Leuven, Leuven, Belgium.

出版信息

Ocul Immunol Inflamm. 2020;28(1):39-42. doi: 10.1080/09273948.2019.1623268. Epub 2019 Aug 15.

Abstract

: The purpose of this report is to describe a case of bilateral Candida chorioretinitis complicated with choroidal neovascularization (CNV) and effectively treated with combined intravitreal bevacizumab and amphotericin B.: An 83-year-old patient was diagnosed with Candida chorioretinitis in both eyes. Optical coherence tomography and fluorescein angiography revealed CNV. Treatment using combined intravitreal bevacizumab and amphotericin B was initiated followed by a 4-weekly regimen of bevacizumab, eventually resulting in the regression of the subretinal fluid and intraretinal edema.: Our study supports the combined use of intravitreal bevacizumab and amphotericin B in the management of CNV in Candida chorioretinitis.

摘要

本报告旨在描述一例双侧念珠菌性脉络膜炎合并脉络膜新生血管(CNV)的病例,并通过玻璃体腔注射贝伐单抗联合两性霉素 B 治疗取得了良好效果。

一名 83 岁患者被诊断为双眼念珠菌性脉络膜炎。光学相干断层扫描和荧光素血管造影显示存在脉络膜新生血管。我们采用玻璃体腔注射贝伐单抗联合两性霉素 B 进行治疗,随后每周进行一次贝伐单抗治疗,最终使视网膜下液和视网膜内水肿消退。

我们的研究支持在念珠菌性脉络膜炎合并脉络膜新生血管患者的治疗中联合使用玻璃体腔注射贝伐单抗和两性霉素 B。

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