Iuga Andra-Iza, Doerner Jonas, Siedek Florian, Haneder Stefan, Byrtus Jonathan, Luetkens Julian A, Maintz David, Hickethier Tilman
Institute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne.
Institute of Diagnostic and Interventional Radiology, University of Bonn, Bonn, Germany.
Medicine (Baltimore). 2019 Aug;98(33):e16606. doi: 10.1097/MD.0000000000016606.
The aim of this study was to determine optimal window settings for conventional polyenergetic and virtual monoenergetic images derived from computed tomography pulmonary angiogram (CTPA) examinations of a novel dual-layer spectral detector computed tomography system (DLCT).
Monoenergetic (40 keV) and polyenergetic images of 50 CTPA examinations were calculated and the best individual window width and level (W/L) values were manually assessed. Optimized values were obtained afterwards based on regression analysis. Diameters of standardized pulmonary artery segments and subjective image quality parameters were evaluated and compared.
Attenuation and contrast-to-noise values were higher in monoenergetic than in polyenergetic images (P≤.001). Averaged best individual W/L for polyenergetic and monoenergetic were 1020/170 and 2070/480 HU, respectively.All adjusted W/L-settings varied significantly compared to standard settings (700/100 HU) and obtained higher subjective image quality scores. A systematic overestimation of artery diameters for standard window settings in monoenergetic images was observed.
Appropriate W/L-settings are required to assess polyenergetic and monoenergetic CTPA images of a novel DLCT. W/L-settings of 1020/170 HU and 2070/480 HU were found to be the best averaged values for polyenergetic and monoenergetic CTPA images, respectively.
本研究旨在确定新型双层光谱探测器计算机断层扫描系统(DLCT)的计算机断层扫描肺血管造影(CTPA)检查所获得的传统多能图像和虚拟单能图像的最佳窗宽设置。
计算50例CTPA检查的单能(40keV)和多能图像,并手动评估最佳的个体窗宽和窗位(W/L)值。随后基于回归分析获得优化值。评估并比较标准化肺动脉段的直径和主观图像质量参数。
单能图像的衰减和对比噪声值高于多能图像(P≤.001)。多能和单能图像的平均最佳个体W/L分别为1020/170和2070/480HU。与标准设置(700/100HU)相比,所有调整后的W/L设置均有显著差异,且获得了更高的主观图像质量评分。观察到单能图像中标准窗设置对动脉直径的系统性高估。
评估新型DLCT的多能和单能CTPA图像需要合适的W/L设置。发现1020/170HU和2070/480HU的W/L设置分别是多能和单能CTPA图像的最佳平均值。