Motulsky Elie H, Liu Guanghui, Shi Yingying, Zheng Fang, Flynn Harry W, Gregori Giovanni, Rosenfeld Philip J
Ophthalmic Surg Lasers Imaging Retina. 2019 Aug 1;50(8):474-484. doi: 10.3928/23258160-20190806-01.
To demonstrate the utility of widefield swept-source optical coherence tomography angiography (SS-OCTA) for the diagnosis and management of proliferative diabetic retinopathy (PDR).
Consecutive patients with vision-threatening diabetic retinopathy were imaged with widefield SS-OCTA using the 12 mm × 12 mm scan pattern.
Twenty-four eyes of 12 patients underwent SS-OCTA imaging. In all 24 eyes, the en face total retinal flow images detected areas of decreased retinal perfusion, and the en face vitreoretinal interface (VRI) slabs detected foci of retinal neovascularization (NV). NV was treated and followed using the VRI images.
Widefield SS-OCTA is a useful, noninvasive technology for the detection and monitoring of NV in PDR. Features of interest, such as areas of decreased retinal perfusion, increased retinal thickness, and NV, can be identified from different en face slabs extracted from a single 12 mm × 12 mm scan. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:474-484.].
证明广角扫频源光学相干断层扫描血管造影（SS-OCTA）在增殖性糖尿病视网膜病变（PDR）诊断和治疗中的应用价值。
采用12mm×12mm扫描模式，对有视力威胁的糖尿病视网膜病变患者进行连续广角SS-OCTA成像。
12例患者的24只眼接受了SS-OCTA成像。在所有24只眼中，视网膜全层血流图像检测到视网膜灌注减少区域，玻璃体视网膜界面（VRI）平板图像检测到视网膜新生血管（NV）病灶。利用VRI图像对NV进行治疗和随访。
广角SS-OCTA是一种用于检测和监测PDR中NV的有用的非侵入性技术。从单次12mm×12mm扫描提取的不同视网膜全层平板图像中，可以识别出感兴趣的特征，如视网膜灌注减少区域、视网膜厚度增加以及NV。[《眼科手术、激光与视网膜成像》。2019；50：474-484。]
