The Mind Research Network and Lovelace Biomedical and Environmental Research Institute, Albuquerque, New Mexico, United States; University of New Mexico, Albuquerque, New Mexico, United States.
The Mind Research Network and Lovelace Biomedical and Environmental Research Institute, Albuquerque, New Mexico, United States.
Biol Psychol. 2019 Nov;148:107740. doi: 10.1016/j.biopsycho.2019.107740. Epub 2019 Aug 12.
Although men commit more crime and are incarcerated at higher rates than women, women represent the fastest growing segment of the justice system. Empirical work suggests that psychopathy and Cluster B disorders are implicated in antisocial behavior across gender, and that neurobiological correlates of personality may inform such behavior. This review utilizes a gendered perspective to discuss psychopathy and Cluster B disorders in relation to antisocial behavior and incorporates work on neural correlates of personality disorders. Co-morbidity across these conditions may be partly explained by similar frontal deficits, reflective of disinhibition. Affective processing abnormalities appear to be characterized by distinct deficits in limbic/paralimbic regions, reflecting differential etiological underpinnings and behavioral outcomes. This review underscores the utility in examining personality pathology together with neurobiological and environmental factors. Methodological issues and clinical implications are also discussed.
尽管男性犯罪率和监禁率高于女性，但女性在司法系统中增长最快。实证研究表明，精神病态和 B 群人格障碍与跨性别反社会行为有关，而人格的神经生物学相关因素可能会影响这种行为。本综述利用性别视角讨论了精神病态和 B 群人格障碍与反社会行为的关系，并结合了人格障碍神经相关的研究工作。这些疾病的共病可能部分可以用相似的额叶缺陷来解释，这反映了抑制功能的丧失。情感处理异常似乎以边缘/边缘系统区域的不同缺陷为特征，反映了不同的病因学基础和行为结果。本综述强调了一起检查人格病理与神经生物学和环境因素的实用性。还讨论了方法学问题和临床意义。
