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巨大肋骨骨肉瘤的根治性切除及复杂胸壁重建术。

Radical resection of a giant rib osteosarcoma with complex chest wall reconstruction.

作者信息

Ahmad Sarwat B, Hoellwarth Jason, Christie Neil, Mcgough Richard

机构信息

Division of Surgical Oncology, Department of Surgery, University of Pittsburgh School of Medicine, 5230 Centre Ave, Pittsburgh, PA 15232, USA.

Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, 5230 Centre Ave, Pittsburgh, PA 15232, USA.

出版信息

Int J Surg Case Rep. 2019;62:17-20. doi: 10.1016/j.ijscr.2019.07.080. Epub 2019 Aug 8.

Abstract

INTRODUCTION

Primary rib osteosarcoma is a rare chest wall tumor with variable presentation. Large tumors greater than 10 cm are even rarer and present a challenge for surgical management.

PRESENTATION OF CASE

A 61-year-old male with a giant osteosarcoma of the left 2 rib underwent multidisciplinary management including induction therapy with doxorubicin and cisplatin, followed by en bloc resection with left ribs 1-5, spinous processes of ribs 2-5, small volume lung resection, and chest wall reconstruction with polypropylene mesh and poly methyl methacrylate (PMMA or bone cement). There were no perioperative complications. At 6 months follow-up, the patient remains disease-free. Functional and cosmetic outcome are excellent.

DISCUSSION

This 20 cm mass and resection of ribs 1-5 with resulting 25 cm chest wall defect is the largest primary rib osteosarcoma reported in literature. An R0 resection and chest wall reconstruction using polypropylene mesh and bone cement was feasible and safe.

CONCLUSION

Giant chest wall defects involving multi-rib resection can be effectively reconstructed with commonly available and inexpensive polypropylene mesh and PMMA to achieve good cosmetic and functional outcomes.

摘要

引言

原发性肋骨骨肉瘤是一种表现多样的罕见胸壁肿瘤。大于10厘米的大肿瘤更为罕见,给手术治疗带来挑战。

病例介绍

一名61岁男性,患有左侧第2肋骨的巨大骨肉瘤,接受了多学科治疗,包括使用阿霉素和顺铂进行诱导治疗,随后整块切除左侧第1 - 5肋骨、第2 - 5肋骨的棘突、小范围肺切除,并使用聚丙烯网片和聚甲基丙烯酸甲酯(PMMA或骨水泥)进行胸壁重建。无围手术期并发症。在6个月的随访中,患者无疾病复发。功能和美容效果极佳。

讨论

这个20厘米的肿块以及切除第1 - 5肋骨导致25厘米的胸壁缺损,是文献报道中最大的原发性肋骨骨肉瘤。使用聚丙烯网片和骨水泥进行R0切除和胸壁重建是可行且安全的。

结论

涉及多根肋骨切除的巨大胸壁缺损,可使用常见且廉价的聚丙烯网片和PMMA进行有效重建,以实现良好的美容和功能效果。

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