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巨大胸壁软骨肉瘤手术治疗方法的病例报告。

Case report on the approach to surgical management for a large chest wall chondrosarcoma.

作者信息

Ramsingh Kimberly, Mohammed Fayard, Hassranah Dale, Ramnarine Ian

机构信息

Department of Surgery- Cardiothoracic Unit, University of the West Indies, Eric Williams Medical Sciences Complex, Trinidad and Tobago.

Department of Surgery- Plastic Surgery Unit, Port of Spain General Hospital, Trinidad and Tobago.

出版信息

Int J Surg Case Rep. 2022 May;94:107047. doi: 10.1016/j.ijscr.2022.107047. Epub 2022 Apr 8.

Abstract

INTRODUCTION AND IMPORTANCE

Primary chest wall tumours are uncommon. Challenges arise in management due to delays in diagnosis and timing of treatment. The mainstay of treatment remains complete resection as adjuvant therapy has a limited role. Choice of repair and materials for chest wall reconstruction vary depending on the size and location of the defect. There are no published reports on management of chondrosarcomas arising from the rib in the Caribbean.

CASE PRESENTATION

A 61-year-old female was referred from a rural clinic with a 10-month history of a progressively enlarging, painless right anterior chest wall lump. Computed Tomography (CT) shows features of a conventional chondrosarcoma arising from the ribs and including surrounding soft tissue, muscle and pleura. Surgical specimen confirms a grade 2 chondrosarcoma.

CLINICAL DISCUSSION

This case illustrates the importance of a multidisciplinary team discussion. Differentiating a chondrosarcoma from a benign cartilaginous tumour requires consideration of clinical features, radiological characteristics and histological features. Chest wall reconstruction aims to preserve functional and structural integrity with adequate soft tissue coverage. The patient had good cosmesis as well as pulmonary function postoperatively and no recurrence at the 3 year follow up.

CONCLUSION

This case highlights that the MDT is essential to a good outcome for the surgical management of a chest wall chondrosarcoma. Wide en-bloc resection followed by reconstruction using polypropylene mesh and a latissimus dorsi flap as a one-stage procedure can be successful.

摘要

引言与重要性

原发性胸壁肿瘤并不常见。由于诊断延迟和治疗时机问题,治疗面临挑战。治疗的主要手段仍然是完整切除,因为辅助治疗作用有限。胸壁重建的修复方式和材料选择因缺损的大小和位置而异。加勒比地区尚无关于肋骨软骨肉瘤治疗的公开报道。

病例介绍

一名61岁女性从农村诊所转诊而来,有一个逐渐增大的、无痛的右前胸壁肿块,病史10个月。计算机断层扫描(CT)显示为起源于肋骨的传统型软骨肉瘤,累及周围软组织、肌肉和胸膜。手术标本证实为2级软骨肉瘤。

临床讨论

本病例说明了多学科团队讨论的重要性。区分软骨肉瘤和良性软骨肿瘤需要考虑临床特征、放射学特征和组织学特征。胸壁重建旨在通过充分的软组织覆盖来保持功能和结构的完整性。患者术后美容效果良好,肺功能正常,3年随访无复发。

结论

本病例强调,多学科团队对于胸壁软骨肉瘤手术治疗取得良好疗效至关重要。采用聚丙烯网片和背阔肌皮瓣进行一期广泛整块切除并重建可获成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a948/9046806/67a5e0128935/gr1.jpg

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