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通过非侵入性测量碳氧血红蛋白检测隐匿性 CO 中毒:一项横断面研究。

The detection of occult CO poisoning through noninvasive measurement of carboxyhemoglobin: A cross-sectional study.

机构信息

Tokat Gaziosmanpasa University, Medicine of Faculty, Emergency Medicine Department, Tokat, Turkey.

Kayseri Training and Research Hospital, Emergency Medicine, Kayseri, Turkey.

出版信息

Am J Emerg Med. 2020 Jun;38(6):1110-1114. doi: 10.1016/j.ajem.2019.158383. Epub 2019 Aug 1.

DOI:10.1016/j.ajem.2019.158383
PMID:31416641
Abstract

OBJECTIVES

Carbon monoxide (CO) poisoning is one of the leading causes of preventable death in the world. Our primary objective was to identify and treat individuals who are unaware of their exposure to carbon monoxide in emergency departments (EDs). Our secondary goal was to reduce the costs of diagnosis and treatment by preventing unnecessary diagnostic testing in EDs.

METHODS

In this cross-sectional study, carboxyhemoglobin (COHb) levels of patients presented with the signs of CO poisoning to the Emergency Department of Kayseri Training and Research Hospital between November 2012 and May 2013 were noninvasively measured during triage. Patients with elevated COHb levels were suspected of CO poisoning and subjected to further investigation.

RESULTS

A total of 4073 patients were enrolled in the study, and 106 (2.6%) of them were diagnosed with CO poisoning. Initial evaluation revealed headache to be the most common presenting complaint in patients with occult CO poisoning. Further evaluations to determine the accuracy of noninvasive measurements showed that noninvasive pulse CO-oxymeter and arterial blood gas (ABG) measurement were compatible.

CONCLUSIONS

The use of noninvasive pulse CO-oxymeter might reduce the morbidity and mortality associated with occult CO poisoning in patients presented with suspected CO poisoning in emergency settings.

摘要

目的

一氧化碳(CO)中毒是世界上可预防死亡的主要原因之一。我们的主要目标是在急诊科(ED)发现并治疗那些不知道自己暴露于一氧化碳的人。我们的次要目标是通过避免在 ED 进行不必要的诊断性检查来降低诊断和治疗的成本。

方法

在这项横断面研究中,2012 年 11 月至 2013 年 5 月期间,我们在凯塞里培训和研究医院急诊科对出现 CO 中毒迹象的患者进行了非侵入性的初筛,测量了其血液中碳氧血红蛋白(COHb)的水平。COHb 水平升高的患者被怀疑患有 CO 中毒,并接受了进一步的检查。

结果

共有 4073 名患者入组该研究,其中 106 名(2.6%)被诊断为 CO 中毒。初步评估显示,隐匿性 CO 中毒患者的最常见首发症状是头痛。为了确定非侵入性测量的准确性,我们进行了进一步的评估,结果表明,非侵入性脉搏 CO 血氧仪和动脉血气(ABG)测量是一致的。

结论

在急诊科出现疑似 CO 中毒的患者中,使用非侵入性脉搏 CO 血氧仪可能会降低隐匿性 CO 中毒相关的发病率和死亡率。

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