Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
Arthroscopy. 2019 Sep;35(9):2709-2721. doi: 10.1016/j.arthro.2019.03.045. Epub 2019 Aug 12.
This review explores the current literature regarding both the clinical indications and utility of minimally invasive in-office needle arthroscopy (IONA) relative to conventional imaging modalities.
In compliance with R-AMSTAR (Revised Assessment of Multiple Systematic Reviews) and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines, 3 databases (MEDLINE, Embase, and PubMed) were searched in July 2018, in addition to the conference abstract databases of 5 prominent meetings between 2013 and 2018, for studies using IONA for diagnostic purposes. Study quality was assessed with the Methodological Index for Non-Randomized Studies (MINORS) criteria.
Among 932 conference abstracts and 369 studies identified, 11 publications involving 404 patients (395 knees and 9 shoulders) were included, with 9 clinical studies and 2 cost analyses. The median Methodological Index for Non-Randomized Studies (MINORS) score was 9 for noncomparative and 23 for comparative studies. Among the 9 clinical studies, IONA had a superior sensitivity, specificity, positive predictive value, and negative predictive value to magnetic resonance imaging (MRI) in the evaluation of knee osteoarthritis, anterior cruciate ligament insufficiency, and meniscal tears. IONA was comparable or inferior to MRI in the same parameters for the diagnosis of osteochondral defects and rotator cuff tears. In the 2 cost analyses, IONA had lower costs when used in place of MRI for treatment algorithms involving medial meniscal tears and rotator cuff tears but not lateral meniscal tears.
IONA holds potential for cost savings and improved diagnostic accuracy relative to MRI, primarily for intra-articular meniscal, ligamentous, and chondral defects of the knee. However, its current indications for use in other joints are limited to rotator cuff tears in the shoulder, making its diagnostic value in other joints much more limited. The current quality and breadth of evidence are significantly lacking, with numerous practical shortcomings. To improve acceptance of IONA, priority should be placed on establishing defined protocols, indications, contraindications, and patient perspectives for the procedure.
Level IV, systematic review of Level II, III, and IV studies.
本综述探讨了微创门诊关节镜检查(IONA)在诊断和治疗中的临床应用和效用,涉及常规影像学检查。
根据 R-AMSTAR(修订的多项系统评价评估)和 PRISMA(系统评价和荟萃分析的首选报告项目)指南,于 2018 年 7 月在 MEDLINE、Embase 和 PubMed 数据库进行了搜索,同时还对 2013 年至 2018 年的 5 次重要会议的会议摘要数据库进行了搜索,以寻找使用 IONA 进行诊断目的的研究。使用非随机研究方法学指数(MINORS)标准评估研究质量。
在 932 篇会议摘要和 369 项研究中,共纳入 11 项研究,涉及 404 例患者(395 个膝关节和 9 个肩关节),其中 9 项为临床研究,2 项为成本分析。非比较性和比较性研究的中位数 MINORS 评分分别为 9 分和 23 分。在 9 项临床研究中,在评估膝关节骨关节炎、前交叉韧带功能不全和半月板撕裂时,IONA 对 MRI 的敏感性、特异性、阳性预测值和阴性预测值均更高。IONA 在诊断骨软骨缺损和肩袖撕裂方面,与 MRI 相比,敏感性、特异性、阳性预测值和阴性预测值相当或更低。在 2 项成本分析中,IONA 替代 MRI 用于内侧半月板撕裂和肩袖撕裂的治疗方案时,成本更低,但对于外侧半月板撕裂则并非如此。
与 MRI 相比,IONA 具有节省成本和提高诊断准确性的潜力,主要适用于膝关节的关节内半月板、韧带和软骨缺损。然而,目前其在其他关节的适应证仅限于肩袖撕裂,因此其在其他关节的诊断价值有限。目前的证据质量和广度明显不足,存在许多实际缺陷。为了提高 IONA 的接受度,应优先制定明确的协议、适应证、禁忌证和患者对该手术的看法。
IV 级,对 II、III 和 IV 级研究的系统评价。