Iftikhar Hassaan, Saleem Maryam, Kaji Anand
Internal Medicine, St. Francis Medical Center, Seton Hall University, Trenton, USA.
Internal Medicine, Waterbury Hospital, Waterbury, USA.
Cureus. 2019 Jun 10;11(6):e4870. doi: 10.7759/cureus.4870.
Pernicious anemia (PA) is a common cause of megaloblastic anemia throughout the world, especially in Northern European whites. This disease is characterized by the deficiency of vitamin B12 due to the presence of anti-intrinsic factor and anti-parietal cell antibodies which inhibit the absorption of the vitamin B12. In cases of severe vitamin B12 deficiency, patients can suffer debilitating complications such as described in our case.
恶性贫血(PA)是全球巨幼细胞贫血的常见病因,在北欧白人中尤为常见。这种疾病的特征是由于存在抗内因子和抗壁细胞抗体,抑制了维生素B12的吸收,从而导致维生素B12缺乏。在严重维生素B12缺乏的情况下,患者可能会出现如我们病例中所述的使人衰弱的并发症。