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技术说明:在不同磁场强度下平行 MRI-直线加速器中剂量沉积的实验特性。

Technical Note: Experimental characterization of the dose deposition in parallel MRI-linacs at various magnetic field strengths.

机构信息

Department of Medical Physics, Liverpool and Macarthur Cancer Therapy Centre, Liverpool, NSW, 2170, Australia.

Ingham Institute for Applied Medical Research, Liverpool, NSW, 2170, Australia.

出版信息

Med Phys. 2019 Nov;46(11):5152-5158. doi: 10.1002/mp.13767. Epub 2019 Sep 9.

Abstract

PURPOSE

Dose deposition measurements for parallel MRI-linacs have previously only shown comparisons between 0 T and a single available magnetic field. The Australian MRI-Linac consists of a magnet coupled with a dual energy linear accelerator and a 120 leaf Multi-Leaf Collimator with the radiation beam parallel to the magnetic field. Two different magnets, with field strengths of 1 and 1.5 T, were used during prototyping. This work aims to characterize the impact of the magnetic field at 1 and 1.5 T on dose deposition, possible by comparing dosimetry measured at both magnetic field strengths to measurements without the magnetic field.

METHODS

Dose deposition measurements focused on a comparison of beam quality (TPR ), PDD, profiles at various depths, surface doses, and field size output factors. Measurements were acquired at 0, 1, and 1.5 T. Beam quality was measured using an ion chamber in solid water at isocenter with appropriate TPR buildup. PDDs and profiles were acquired via EBT3 film placed in solid water either parallel or perpendicular to the radiation beam. Films at surface were used to determine surface dose. Output factors were measured in solid water using an ion chamber at isocenter with 10 cm solid water buildup.

RESULTS

Beam quality was within ±0.5% of the 0 T value for the 1 and 1.5 T magnetic field strengths. PDDs and profiles showed agreement for the three magnetic field strengths at depths beyond 20 mm. Deposited dose increased at shallower depths due to electron focusing. Output factors showed agreement within 1%.

CONCLUSION

Dose deposition at depth for a parallel MRI-linac was not significantly impacted by either a 1 or 1.5 T magnetic field. PDDs and profiles at shallow depths and surface dose measurements showed significant differences between 0, 1, and 1.5 T due to electron focusing.

摘要

目的

以前,并行 MRI-直线加速器的剂量沉积测量仅比较了 0 T 和单个可用磁场。澳大利亚的 MRI-直线加速器由一个与双能线性加速器耦合的磁铁和一个 120 叶多叶准直器组成,辐射束与磁场平行。在原型制作过程中使用了两个不同的磁场,磁场强度分别为 1 T 和 1.5 T。这项工作旨在通过比较两种磁场强度下的剂量沉积测量值与无磁场时的测量值,来确定磁场在 1 T 和 1.5 T 下对剂量沉积的影响。

方法

剂量沉积测量集中于比较束质(TPR )、PDD、各种深度的剖面、表面剂量和射野输出因子。在 0 T、1 T 和 1.5 T 下进行了测量。在等中心使用水中电离室测量束质,使用适当的 TPR 建立来测量 TPR。在水中使用 EBT3 胶片平行或垂直于辐射束进行 PDD 和剖面的测量。在表面上使用胶片确定表面剂量。在等中心使用水中的电离室,在 10 cm 水的积累下测量输出因子。

结果

在 1 T 和 1.5 T 磁场强度下,束质在±0.5%的范围内与 0 T 值相同。在深度超过 20 mm 时,三种磁场强度的 PDD 和剖面一致。由于电子聚焦,在较浅的深度处沉积剂量增加。输出因子在 1%以内一致。

结论

在并行 MRI-直线加速器中,深度处的剂量沉积受 1 T 或 1.5 T 磁场的影响不大。由于电子聚焦,在较浅的深度、表面剂量测量值以及 PDD 和剖面之间存在显著差异。

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