Department of Pathology, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal.
Department of Pathology, Centro Hospitalar S. João, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Virchows Arch. 2019 Oct;475(4):499-511. doi: 10.1007/s00428-019-02639-0. Epub 2019 Aug 16.
Fetal and perinatal growth charts and tables are essential for proper interpretation of autopsy anthropometric parameters. These parameters depend on factors that may vary between populations; thus, it is recommended that standards be developed from local target populations to ensure that they are truly representative. In this study, we established standards for a complete set of autopsy fetal parameters, including biometrical measurements, organ weights and long bone lengths, based on autopsy data collected retrospectively from a sample of Portuguese fetuses and neonates. Using a robust statistical regression methodology, to fit mean and standard deviation models, we constructed growth curves for gestational ages between 12 and 42 weeks, which aim to be useful for autopsy examination, particularly in the Portuguese population.
胎儿和围产儿生长图表和表格对于正确解释尸检人体测量参数至关重要。这些参数取决于人群中可能存在差异的因素;因此,建议从当地目标人群中制定标准,以确保其具有真正的代表性。在这项研究中,我们根据从葡萄牙胎儿和新生儿的尸检数据中收集的样本,建立了一套完整的尸检胎儿参数标准,包括生物测量、器官重量和长骨长度。我们使用稳健的统计回归方法来拟合均值和标准差模型,构建了 12 至 42 周胎龄的生长曲线,旨在为尸检检查提供有用的信息,特别是在葡萄牙人群中。