Department of Oral Pathology, Private Bag 3, South Africa,
Med Oral Patol Oral Cir Bucal. 2019 Sep 1;24(5):e571-e576. doi: 10.4317/medoral.22873.
To compare the histologic diagnosis of lesions associated with impacted teeth from a South African population with literature data.
A retrospective cross-sectional survey of tissue specimens associated with impacted teeth that were analyzed in the Department of Oral Pathology (University of the Witwatersrand, South Africa) between 1996 and 2016. Patient age, gender, impacted tooth location and the histologic diagnosis were recorded for statistical analysis.
Odontogenic pathology was diagnosed in 389 (95.6%) specimens while dental follicle comprised 4.4% of tissue submissions. The mean age was 25.3 ±15.2 years with a male predilection (M:F=1.8:1). The 11-20 year age group was mostly affected and the overall frequency of odontogenic lesions reduced significantly with an increase in age (p=0.01). Dentigerous cyst (56.5%) and ameloblastoma (14%) were most commonly diagnosed.
This is the first African epidemiologic survey of histologic specimens associated with impacted teeth and shows striking differences in the ratio of pathologic to non-pathologic diagnoses compared to other populations. Locally aggressive odontogenic lesions appear to develop one to two decades earlier in patients from developing countries.
比较南非人群中与埋伏牙相关病变的组织学诊断与文献数据。
回顾性分析 1996 年至 2016 年间在南非威特沃特斯兰德大学口腔病理学系（University of the Witwatersrand）分析的与埋伏牙相关的组织标本。记录患者年龄、性别、埋伏牙位置和组织学诊断，进行统计学分析。
389 份（95.6%）标本诊断为牙源性病变，而牙滤泡占组织送检的 4.4%。平均年龄为 25.3±15.2 岁，男性偏多（M:F=1.8:1）。11-20 岁年龄组受影响最大，随着年龄的增长，牙源性病变的总体频率显著降低（p=0.01）。牙源性囊肿（56.5%）和造釉细胞瘤（14%）最常被诊断。
这是首次对与埋伏牙相关的组织学标本进行的非洲流行病学调查，与其他人群相比，病理与非病理诊断的比例存在显著差异。在发展中国家的患者中，局部侵袭性牙源性病变似乎在 10 到 20 年内更早出现。
