Mutio Joseph, Dimba Elizabeth, Sarna Krishan, Sonigra Khushboo, Twahir Wambeti, Ndui Kanini, Lukandu Ochiba O, Odhiambo Walter, Ngeow Wei Cheong
Department of Oral and Maxillofacial Surgery, Oral Pathology, and Oral Medicine, Division of Oral Pathology, University of Nairobi, Nairobi, KEN.
Department of Oral and Maxillofacial Surgery, Oral Pathology, and Oral Medicine, Division of Oral and Maxillofacial Surgery, University of Nairobi, Nairobi, KEN.
Cureus. 2024 Sep 29;16(9):e70471. doi: 10.7759/cureus.70471. eCollection 2024 Sep.
This study endeavors to bridge the long-term diagnostic and management gap through a comprehensive audit of odontogenic cysts and tumors in Kenya, offering crucial insights for both clinicians and policymakers.
Patient records (2001-2020) with odontogenic cysts and tumors were retrospectively abstracted from two major referral hospitals in Nairobi, Kenya, covering demographics, lesion location, and histological diagnosis. IBM SPSS Statistics for Windows, Version 29.0 (Released 2023; IBM Corp., Armonk, New York, United States) was used for data analysis which included all descriptive statistics, student t-tests, chi-square tests, and one-way ANOVA.
A total of 1889 cases were analyzed. Males exhibited a significantly higher prevalence of cysts and tumors (p < 0.001). Odontogenic tumors dominated in the age group of 21-30 years, while cysts were prevalent in the age group of 11-20 years. Ameloblastoma was the most prevalent tumor (n=853; 84.1%) while dentigerous cysts were the most common cysts (n = 468; 53.5%), both demonstrating a male predilection. The mean age at presentation and site predilection of each tumor and cyst were also detailed.
This study provides crucial insights into odontogenic cysts and tumors in Kenya emphasizing geographic variations, age-specific patterns, and gender disparities for more effective diagnostic and management strategies, especially in resource-limited settings, to improve outcomes and reduce associated morbidity and mortality.
本研究旨在通过对肯尼亚牙源性囊肿和肿瘤进行全面审计，弥合长期存在的诊断和管理差距，为临床医生和政策制定者提供关键见解。
回顾性提取肯尼亚内罗毕两家主要转诊医院2001年至2020年患有牙源性囊肿和肿瘤的患者记录，涵盖人口统计学、病变位置和组织学诊断。使用IBM SPSS Statistics for Windows 29.0版（2023年发布；IBM公司，美国纽约州阿蒙克）进行数据分析，包括所有描述性统计、学生t检验、卡方检验和单因素方差分析。
共分析了1889例病例。男性囊肿和肿瘤的患病率显著更高（p < 0.001）。牙源性肿瘤在21至30岁年龄组中占主导地位，而囊肿在11至20岁年龄组中更为普遍。成釉细胞瘤是最常见的肿瘤（n = 853；84.1%），而含牙囊肿是最常见的囊肿（n = 468；53.5%），两者均表现出男性偏好。还详细列出了每种肿瘤和囊肿的平均就诊年龄和部位偏好。
本研究为肯尼亚牙源性囊肿和肿瘤提供了关键见解，强调了地理差异、年龄特异性模式和性别差异，以制定更有效的诊断和管理策略，特别是在资源有限的环境中，以改善治疗效果并降低相关的发病率和死亡率。
