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原发性上腹部疝的手术治疗的系统评价。

A systematic review on surgical treatment of primary epigastric hernias.

机构信息

Department of Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

Department of Surgery, Tergooi, Van Riebeeckweg 212, 1213 XZ, Hilversum, The Netherlands.

出版信息

Hernia. 2019 Oct;23(5):847-857. doi: 10.1007/s10029-019-02017-4. Epub 2019 Aug 17.

Abstract

OBJECTIVE

In this systematic review, we evaluated all literature reporting on the surgical treatment of primary epigastric hernias, primarily focusing on studies comparing laparoscopic and open repair, and mesh reinforcement and suture repair.

METHODS

A literature search was conducted in Embase.com, PubMed and the Cochrane Library up to 24 April 2019. This review explicitly excluded literature on incisional hernias, ventral hernias not otherwise specified, and isolated (para)umbilical hernias. Primary outcome measures of interest were early and late postoperative complications.

RESULTS

We obtained a total of 8516 articles and after a strict selection only seven retrospective studies and one randomised controlled trial (RCT) on treatment of primary epigastric hernia were included. In one study (RCT) laparoscopic repair led to less postoperative pain (VAS) compared to open repair (3.6 versus 2.4, p < 0.001). No significant differences in early postoperative complications and recurrences were observed. Mesh reinforcement was associated with lower recurrence rates than suture repair in two studies (2.2% versus 5.6%, p  = 0.001 and 3.1% versus 14.7%, p = 0.0475). This result was not sustained in all studies. No differences were observed in early postoperative complications after mesh or suture repair.

CONCLUSIONS

This review demonstrated that studies investigating surgical treatment of primary epigastric hernias are scarce. The best available evidence suggests that mesh reinforcement in primary epigastric hernia repair possibily leads to less recurrences and that laparoscopic repair leads to less postoperative pain. Due to the high risk of selection bias of included studies and heterogenic study populations, no clear recommendations can be conducted. High-quality studies with well-defined patient groups and clear endpoints, primarily focusing on primary epigastric hernias, are mandatory.

摘要

目的

在这项系统评价中,我们评估了所有报告原发性上腹部疝外科治疗的文献,主要侧重于比较腹腔镜和开放修补术以及网片加固和缝合修补术的研究。

方法

我们在 Embase.com、PubMed 和 Cochrane Library 进行了文献检索,检索时间截至 2019 年 4 月 24 日。本综述明确排除了切口疝、未特指的腹侧疝和孤立的(para)脐疝文献。主要观察指标为术后早期和晚期并发症。

结果

我们共获得了 8516 篇文章,经过严格筛选,仅纳入了 7 项关于原发性上腹部疝治疗的回顾性研究和 1 项随机对照试验(RCT)。在一项研究(RCT)中,与开放修补术相比,腹腔镜修补术导致的术后疼痛(VAS)较轻(3.6 对 2.4,p<0.001)。两组患者的早期术后并发症和复发率无显著差异。在两项研究中,网片加固与缝合修补术相比,复发率较低(2.2%对 5.6%,p=0.001 和 3.1%对 14.7%,p=0.0475)。但这一结果并非在所有研究中都成立。网片或缝合修补术后早期并发症无差异。

结论

本综述表明,研究原发性上腹部疝外科治疗的文献稀缺。现有最佳证据表明,网片加固可能导致原发性上腹部疝修补术后复发率降低,腹腔镜修补术导致术后疼痛减轻。由于纳入研究的选择偏倚风险高且研究人群异质性大,因此无法提出明确的建议。需要开展高质量的研究,明确定义患者群体和明确的研究终点,主要关注原发性上腹部疝。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/add9/6838029/1e15e5fb284e/10029_2019_2017_Fig1_HTML.jpg

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