用氙 - 133吸入断层扫描研究震颤谵妄及相关临床状态期间的脑血流量。

Cerebral blood flow during delirium tremens and related clinical states studied with xenon-133 inhalation tomography.

作者信息

Hemmingsen R, Vorstrup S, Clemmesen L, Holm S, Tfelt-Hansen P, Sørensen A S, Hansen C, Sommer W, Bolwig T G

机构信息

Department of Psychiatry, Copenhagen University Hospital, Denmark.

出版信息

Am J Psychiatry. 1988 Nov;145(11):1384-90. doi: 10.1176/ajp.145.11.1384.

DOI:10.1176/ajp.145.11.1384

PMID:3142283

Abstract

The regional cerebral blood flow of 12 patients with severe alcohol withdrawal reactions (delirium tremens or impending delirium tremens) was measured during the acute state before treatment and after recovery. Greater cerebral blood flow was significantly correlated with visual hallucinations and agitation during the acute withdrawal reaction. The results suggest that delirium tremens and related clinical states represent a type of acute brain syndrome mainly characterized by CNS hyperexcitability.

摘要

在12例有严重酒精戒断反应（震颤谵妄或即将发生震颤谵妄）的患者处于治疗前的急性期及康复后，测量其局部脑血流量。在急性戒断反应期间，较高的脑血流量与视幻觉及激越显著相关。结果提示，震颤谵妄及相关临床状态代表一种主要以中枢神经系统过度兴奋为特征的急性脑综合征。