Berglund M, Risberg J
Arch Gen Psychiatry. 1981 Mar;38(3):351-5. doi: 10.1001/archpsyc.1981.01780280119014.
Serial bilateral measurements of regional cerebral blood flow (rCBF) by the xenon Xe 133 inhalation method were made during 13 withdrawal periods in 12 male alcoholics with pronounced physical dependence. A significant global reduction of rCBF was found during the first two days of withdrawal. The largest decreases were seen in cases with clouded sensorium and with an extended preceding drinking period. An rCBF distribution with relatively high temporal and low parietal flows during the first two days was coupled to aggravated symptoms. In two men who reported auditory and visual hallucinations during the measurements, elevated rCBF values were found in the temporal, Sylvian, and occipital regions.
采用氙Xe 133吸入法，对12名有明显身体依赖的男性酗酒者在13个戒断期进行了双侧局部脑血流量（rCBF）的连续测量。在戒断的前两天发现rCBF有显著的整体降低。在意识模糊和饮酒前期延长的病例中，rCBF下降最为明显。在戒断的前两天，rCBF分布呈现颞叶血流相对较高而顶叶血流较低的情况，这与症状加重有关。在两名测量过程中报告有听觉和视觉幻觉的男性中，在颞叶、大脑外侧裂和枕叶区域发现rCBF值升高。
