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85只犬肥大细胞瘤放射治疗的预后因素

Prognostic factors for radiation treatment of mast cell tumor in 85 dogs.

作者信息

Turrel J M, Kitchell B E, Miller L M, Théon A

机构信息

Department of Radiological Sciences, Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616.

出版信息

J Am Vet Med Assoc. 1988 Oct 15;193(8):936-40.

PMID:3142828
Abstract

Ninety-five mast cell tumors in 85 dogs were therapeutically irradiated. Median and mean tumor-free times for dogs were 17 and 62.7 months, respectively. Percentages of dogs tumor-free at 1 and 2 years were 78.8 and 77%, respectively. Factors significantly affecting tumor-free time were clinical stage (P less than 0.001) and neoplasm location (P = 0.019). Median and mean survival times were 19 and 61.2 months, respectively. Survival rates at 1 and 2 years were 76.2 and 73.2%, respectively. Prognostic factors that significantly affected survival rates were clinical stage (P less than 0.001), neoplasm grade (P = 0.006), and neoplasm location (P = 0.034). Radiation therapy was an effective treatment of mast cell tumor in dogs.

摘要

对85只犬的95个肥大细胞瘤进行了放射治疗。犬的无瘤时间中位数和平均值分别为17个月和62.7个月。1年和2年时无瘤犬的百分比分别为78.8%和77%。显著影响无瘤时间的因素为临床分期(P<0.001)和肿瘤位置(P = 0.019)。中位生存时间和平均生存时间分别为19个月和61.2个月。1年和2年时的生存率分别为76.2%和73.2%。显著影响生存率的预后因素为临床分期(P<0.001)、肿瘤分级(P = 0.006)和肿瘤位置(P = 0.034)。放射治疗是犬肥大细胞瘤的一种有效治疗方法。

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