Seki T, Yoshikawa H, Takahashi H, Saito H
Institute of Applied Microbiology, University of Tokyo, Japan.
J Bacteriol. 1988 Dec;170(12):5935-8. doi: 10.1128/jb.170.12.5935-5938.1988.
The nucleotide sequence of phoR, the positive and negative regulatory gene for alkaline phosphatase and phosphodiesterase formation in Bacillus subtilis, was determined. The sequence data predicted an open reading frame of 1,740 base pairs (579 amino acids) which overlaps the 5 base pairs of the preceding phoP coding sequence. The deduced amino acid sequence was significantly homologous with that of the Escherichia coli phoR gene product, which is the sensory element for the pho regulon.
测定了枯草芽孢杆菌中碱性磷酸酶和磷酸二酯酶形成的正负调控基因phoR的核苷酸序列。序列数据预测有一个1740个碱基对(579个氨基酸)的开放阅读框,它与前面phoP编码序列的5个碱基对重叠。推导的氨基酸序列与大肠杆菌phoR基因产物的序列有显著同源性,后者是pho调节子的传感元件。