Radiation Oncology, Geneva University Hospital, Switzerland; Faculty of Medicine, Geneva University, Switzerland.
Radiation Oncology, Humanitas Research Hospital and Cancer Center, Milan, Italy.
Radiother Oncol. 2019 Oct;139:83-86. doi: 10.1016/j.radonc.2019.07.018. Epub 2019 Aug 17.
The ONE SHOT trial is the first phase I/II prospective, multicenter, single-arm study assessing the efficacy and safety of a single-dose SBRT for men with localized prostate cancer. Aim of this paper is to present the phase I results of a 19 Gy single fraction urethra-sparing SBRT with real-time electromagnetic tracking.
ONE SHOT 试验是首个 I/II 期前瞻性、多中心、单臂研究,旨在评估单次 SBRT 治疗局限性前列腺癌的疗效和安全性。本文旨在介绍 19Gy 单次分割、实时电磁追踪的尿道保护 SBRT 的 I 期结果。