太极拳对慢性疼痛老年患者β-内啡肽和炎症标志物的影响：一项探索性研究。
Effects of Tai Chi on beta endorphin and inflammatory markers in older adults with chronic pain: an exploratory study.
机构信息
Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, 02125, USA.
New England GRECC, VA Boston Healthcare System, Boston, MA, 02130, USA.
出版信息
Aging Clin Exp Res. 2020 Jul;32(7):1389-1392. doi: 10.1007/s40520-019-01316-1. Epub 2019 Aug 20.
The purpose of this exploratory study was to examine the effects of Tai Chi on blood levels of beta endorphin (β-endorphin) and inflammatory markers in older adults with chronic pain. Forty community-dwelling older adults with chronic pain were randomized to Tai Chi or light physical exercise, and each offered twice weekly for 12 weeks. Following the 12-week intervention, neither Tai Chi nor light physical exercise changed levels of β-endorphin and inflammatory markers. However, in older adults who completed 70% or more classes, Tai Chi significantly lowered levels of β-endorphin (p < 0.05), whereas light physical exercise did not change levels of β-endorphin. The results suggest that Tai Chi may reduce levels of β-endorphin in older adults with chronic pain. Future studies are needed to better understand the role of the opioid analgesic system and immune system in regulating pain with aging and the long-term effects of Tai Chi on pain-related biomarkers.
本探索性研究旨在探讨太极拳对慢性疼痛老年患者血液β-内啡肽（β-endorphin）和炎症标志物水平的影响。40 名患有慢性疼痛的社区居住老年人被随机分为太极拳组或轻度体育锻炼组，每组每周进行两次，共 12 周。12 周干预后，太极拳和轻度体育锻炼均未改变β-内啡肽和炎症标志物水平。然而，在完成 70%或更多课程的老年人中，太极拳显著降低了β-内啡肽水平（p<0.05），而轻度体育锻炼并未改变β-内啡肽水平。研究结果表明，太极拳可能会降低慢性疼痛老年患者的β-内啡肽水平。未来的研究需要更好地了解阿片类镇痛系统和免疫系统在衰老过程中调节疼痛的作用，以及太极拳对疼痛相关生物标志物的长期影响。
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