Laskosky Nicole Alexandra, Huston Patricia, Lam Wai Ching, Anderson Charlotte, Zheng Ya, Zhong Linda L D
Department of Family Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Institut du Savoir Montfort (Research), University of Ottawa, Ottawa, ON, Canada.
Front Aging Neurosci. 2023 Mar 6;15:1121064. doi: 10.3389/fnagi.2023.1121064. eCollection 2023.
Traumatic brain injury (TBI) adversely affects both young and old and is a growing public health issue. A number of recent trends in managing TBI, such as recommending sub-threshold aerobic activity, tailoring multi-modal treatment strategies, and studying the possible role of low-grade inflammation in those with persistent symptoms, all suggest that the physical and cognitive exercise of tai chi/qigong could have benefit.
Designed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the following databases will be searched: MEDLINE, CINAHL, Cochrane Library, Embase, China National Knowledge Infrastructure Database, Wanfang Database, Chinese Scientific Journal Database, and Chinese Biomedical Literature Database. All clinical trials on mild, moderate and/or severe TBI with tai chi and/or qigong as the treatment group and any comparison group, in any setting will be included. Four reviewers will independently select studies; two reviewers for the English and two for the Chinese databases. Cochrane-based risk of bias assessments will be conducted on all included studies. An analysis will then be conducted with the grading of recommendation, assessment, development, and evaluation (GRADE) instrument.
This review will summarize the clinical trial evidence on tai chi/qigong for TBI including type of TBI, age/sex of participants, type and length of intervention and comparator, outcome measures, and any adverse events. The risk of bias will be considered, and the strengths and weaknesses of each trial will be analyzed.
The results of this review will be considered with respect to whether there is enough evidence of benefit to merit a more definitive randomized controlled trial. PROSPERO [CRD42022364385].
创伤性脑损伤（TBI）对年轻人和老年人都会产生不利影响，且这一公共卫生问题日益严重。近期在TBI管理方面的一些趋势，如推荐亚阈值有氧运动、定制多模式治疗策略以及研究低度炎症在有持续症状者中的可能作用，均表明太极拳/气功的身体和认知锻炼可能有益。
按照系统评价和Meta分析的首选报告项目（PRISMA）指南进行设计，将检索以下数据库：MEDLINE、CINAHL、Cochrane图书馆、Embase、中国知网数据库、万方数据库、中国科学期刊数据库和中国生物医学文献数据库。纳入所有以太极拳和/或气功为治疗组、在任何环境下与任何对照组进行比较的轻、中、重度TBI临床试验。四位评审员将独立选择研究；两位负责英文数据库，两位负责中文数据库。将对所有纳入研究进行基于Cochrane的偏倚风险评估。然后使用推荐分级、评估、制定和评价（GRADE）工具进行分析。
本综述将总结太极拳/气功治疗TBI的临床试验证据，包括TBI类型、参与者年龄/性别、干预类型和时长以及对照、结局指标和任何不良事件。将考虑偏倚风险，并分析每项试验的优缺点。
将根据是否有足够的益处证据来考虑是否值得进行更明确的随机对照试验，从而对本综述的结果进行考量。国际前瞻性系统评价注册库[CRD42022364385] 。
