部分性癫痫的预后
Prognosis of partial epilepsy.
作者信息
Porro G, Matricardi M, Guidetti V, Benedetti P
机构信息
Instituto di Neuropsichiatria, Rome, Italy.
出版信息
Arch Dis Child. 1988 Oct;63(10):1192-7. doi: 10.1136/adc.63.10.1192.
The prognosis of partial epilepsy in childhood (excluding cases of benign partial epilepsy) was studied; the average follow up period was 7.4 years. Improvement rate of seizure status was 82.3%. We studied favourable prognostic factors and found that those most often associated with seizure improvement were familial convulsions and idiopathic forms, no generalised seizures before partial onset, low frequency of seizures after 12 months of treatment, short duration of epilepsy, and no background activity abnormalities on electroencephalography. We also observed such factors as mental retardation, neurological abnormalities, and behaviour and cognitive disorders. Factors that determined the prognosis for social adjustment were similar to those for seizure improvement. We discuss the favourable prognosis of partial seizures in childhood and the predictive factors.
对儿童部分性癫痫（不包括良性部分性癫痫病例）的预后进行了研究；平均随访期为7.4年。癫痫发作状态的改善率为82.3%。我们研究了有利的预后因素，发现最常与癫痫发作改善相关的因素是家族性惊厥和特发性类型、部分发作前无全身性发作、治疗12个月后癫痫发作频率低、癫痫病程短以及脑电图无背景活动异常。我们还观察到智力迟钝、神经异常以及行为和认知障碍等因素。决定社会适应预后的因素与癫痫发作改善的因素相似。我们讨论了儿童部分性癫痫的良好预后及预测因素。
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