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水动力推进作为犬猫鼻腔癌姑息性、长期、最后手段的治疗方法

Hydropulsion as Palliative, Long-Term, Last-Resort Treatment of Nasal Carcinoma in a Dog and a Cat.

作者信息

Bienes Tom, Robin Elisabeth, Le Boedec Kevin

机构信息

From Veterinary Hospital Frégis, Arcueil, France.

出版信息

J Am Anim Hosp Assoc. 2019 Sep/Oct;55(5):e55501. doi: 10.5326/JAAHA-MS-6901.

DOI:10.5326/JAAHA-MS-6901
PMID:31433223
Abstract

An 8 yr old spayed female domestic shorthair and an 8 yr old neutered male Polish Lowland sheepdog were evaluated for a 3 wk history of sneezing and a 5 day history of left epistaxis, respectively. In both cases, computed tomography revealed a voluminous nasal mass, which was later histologically identified as carcinoma, without cribriform plate involvement. Nasal hydropulsion was performed in both animals in sternal recumbency under general anesthesia. A Poole suction tip was inserted into the orad esophageal opening and adequacy of the endotracheal tube cuff inflation was checked. Sterile saline was forcefully infused into the obstructed nasal cavity to dislodge the tumor. Both patients had temporary resolution of clinical signs. Nasal hydropulsion was repeated as a palliative last-resort treatment at each clinical relapse (four times in both animals over ≥1 yr), allowing long-term survival. Minor complications included a self-limiting retrobulbar and oropharyngeal swelling in the cat and self-limiting epistaxis in both animals. Although this technique is not intended to represent an equivalent alternative to radiation or surgical therapies, nasal hydropulsion may represent an appropriate palliative, last-resort treatment in case of obstructive nasal tumors in dogs and cats, when radiation therapy or surgery is not affordable, available, or desired.

摘要

分别对一只8岁已绝育的雌性家猫和一只8岁已去势的雄性波兰低地牧羊犬进行评估,它们分别有3周的打喷嚏病史和5天的左侧鼻出血病史。在这两个病例中,计算机断层扫描显示鼻腔有一个巨大肿块,后来经组织学鉴定为癌,未累及筛板。在全身麻醉下,让两只动物采取胸骨卧位进行鼻腔水冲法。将一个普尔吸引头插入食管开口处,并检查气管导管套囊充气是否充分。将无菌生理盐水强力注入阻塞的鼻腔以清除肿瘤。两只病畜的临床症状都得到了暂时缓解。在每次临床复发时(两只动物在≥1年的时间里均复发了4次),作为姑息性的最后手段重复进行鼻腔水冲法,从而实现了长期存活。轻微并发症包括猫出现自限性的球后和口咽部肿胀,以及两只动物均出现自限性鼻出血。尽管该技术并非旨在替代放射治疗或手术治疗,但在无法负担、无法进行或不希望进行放射治疗或手术的情况下,鼻腔水冲法可能是犬猫阻塞性鼻腔肿瘤合适的姑息性最后手段治疗方法。

相似文献

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Hydropulsion as Palliative, Long-Term, Last-Resort Treatment of Nasal Carcinoma in a Dog and a Cat.水动力推进作为犬猫鼻腔癌姑息性、长期、最后手段的治疗方法
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