Lee Seon-Kyu, Weiss Brandon, Yanamadala Vijay, Brook Allan
Department of Radiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.
Department of Neurosurgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.
Semin Intervent Radiol. 2019 Aug;36(3):249-254. doi: 10.1055/s-0039-1694698. Epub 2019 Aug 19.
Spinal metastasis is usually associated with debilitating pain and results in deteriorating life quality. The role of percutaneous management of spinal metastasis has evolved from a diagnostic role to a significant part of therapeutic options in conjunction with conventional management techniques, including radiotherapy and open surgical options. Percutaneous vertebral augmentation (PVA) showed substantial pain reduction, vertebral stabilization, and improvement of quality of life. Minimally invasive local ablative procedures (MILAPs) demonstrated significant pain reduction, local tumor burden control, and improvement of quality of life. Though combined PVA and MILAP's synergistic role in pain reduction may need additional investigation, considering different actions on spine metastasis patients, combining both techniques might beneficial to selected patients. The role of percutaneous management will likely expand since its role in improving patient's quality of life with very minimal procedure-related risk and in conjunction with future technological advancement.
脊柱转移瘤通常伴有使人衰弱的疼痛，导致生活质量下降。脊柱转移瘤的经皮治疗作用已从诊断作用演变为与包括放疗和开放手术选择在内的传统治疗技术相结合的重要治疗选择。经皮椎体强化术（PVA）显示出可显著减轻疼痛、稳定椎体并改善生活质量。微创局部消融手术（MILAPs）显示出可显著减轻疼痛、控制局部肿瘤负荷并改善生活质量。尽管PVA和MILAPs联合在减轻疼痛方面的协同作用可能需要进一步研究，但考虑到对脊柱转移瘤患者的不同作用，联合这两种技术可能对部分患者有益。经皮治疗的作用可能会扩大，因为其在以极低的手术相关风险改善患者生活质量方面的作用以及与未来技术进步相结合的作用。
