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本文引用的文献

1
Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus.非酒精性脂肪肝疾病在孕早期与妊娠期糖尿病的后续发展。
Diabetologia. 2019 Feb;62(2):238-248. doi: 10.1007/s00125-018-4779-8. Epub 2018 Nov 23.
2
Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women.哺乳期时间较长与女性非酒精性脂肪肝患病率降低有关。
J Hepatol. 2019 Jan;70(1):126-132. doi: 10.1016/j.jhep.2018.09.013. Epub 2018 Nov 1.
3
Hepatic fat and glucose tolerance in women with recent gestational diabetes.近期患妊娠糖尿病女性的肝脏脂肪与糖耐量
BMJ Open Diabetes Res Care. 2018 Sep 8;6(1):e000549. doi: 10.1136/bmjdrc-2018-000549. eCollection 2018.
4
Impact of non-alcoholic fatty liver disease on pregnancy.非酒精性脂肪性肝病对妊娠的影响。
Br J Biomed Sci. 2018 Oct;75(4):197-199. doi: 10.1080/09674845.2018.1492205. Epub 2018 Aug 6.
5
NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances.NASH 成为女性肝移植首要原因:肝移植适应证的最新分析及种族和性别差异
Am J Gastroenterol. 2018 Nov;113(11):1649-1659. doi: 10.1038/s41395-018-0088-6. Epub 2018 Jun 8.
6
Nonalcoholic fatty liver disease incidence and impact on metabolic burden and death: A 20 year-community study.非酒精性脂肪性肝病的发病率及其对代谢负担和死亡的影响:一项 20 年的社区研究。
Hepatology. 2018 May;67(5):1726-1736. doi: 10.1002/hep.29546. Epub 2018 Mar 23.
7
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases.非酒精性脂肪性肝病的诊断与管理:美国肝病研究协会的实践指南
Hepatology. 2018 Jan;67(1):328-357. doi: 10.1002/hep.29367. Epub 2017 Sep 29.
8
Sex differences between parental pregnancy characteristics and nonalcoholic fatty liver disease in adolescents.父母妊娠特征与青少年非酒精性脂肪性肝病的性别差异。
Hepatology. 2018 Jan;67(1):108-122. doi: 10.1002/hep.29347. Epub 2017 Nov 13.
9
Infant nutrition and maternal obesity influence the risk of non-alcoholic fatty liver disease in adolescents.婴儿营养和产妇肥胖会影响青少年非酒精性脂肪肝的发病风险。
J Hepatol. 2017 Sep;67(3):568-576. doi: 10.1016/j.jhep.2017.03.029. Epub 2017 Jun 12.
10
Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference.非酒精性脂肪性肝病在患有既往妊娠糖尿病的女性中普遍存在,且与胰岛素抵抗和腰围独立相关。
Diabetes Care. 2017 Jan;40(1):109-116. doi: 10.2337/dc16-1017. Epub 2016 Nov 3.

非酒精性脂肪性肝病对妊娠及母婴结局的影响。

Implications of Nonalcoholic Fatty Liver Disease on Pregnancy and Maternal and Child Outcomes.

作者信息

Hershman Melissa, Mei Rena, Kushner Tatyana

机构信息

Dr Hershman is a fellow in the Division of Gastroenterology at Mount Sinai Beth Israel, Mount Sinai St. Luke's, and Mount Sinai West in New York, New York. Ms Mei is a medical student at the Icahn School of Medicine at Mount Sinai in New York, New York. Dr Kushner is an assistant professor of medicine in the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai.

出版信息

Gastroenterol Hepatol (N Y). 2019 Apr;15(4):221-228.

PMID:31435201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6696596/
Abstract

With an estimated 10% prevalence of nonalcoholic fatty liver disease (NAFLD) among women of childbearing age, it is important to understand the implications of this disease on pregnancy. This article explores the relationship between NAFLD and gestational diabetes mellitus, the implications of maternal NAFLD on both the pregnancy and the infant, and the effects of breastfeeding on maternal and offspring health. Prospective studies and sensitive diagnostic techniques for the evaluation of NAFLD during pregnancy are limited; however, emerging evidence suggests that appropriate counseling and monitoring of patients with, or at risk of developing, NAFLD during pregnancy may have significant benefits on maternal and child health.

摘要

据估计,育龄女性中非酒精性脂肪性肝病(NAFLD)的患病率为10%,因此了解这种疾病对妊娠的影响很重要。本文探讨了NAFLD与妊娠期糖尿病之间的关系、母体NAFLD对妊娠和婴儿的影响,以及母乳喂养对母体和后代健康的影响。用于评估孕期NAFLD的前瞻性研究和敏感诊断技术有限;然而,新出现的证据表明,对孕期患有NAFLD或有患NAFLD风险的患者进行适当的咨询和监测,可能对母婴健康有显著益处。