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沙特年轻女性的肥胖、体能、维生素D水平与血流动力学参数之间的关联

The association of adiposity, physical fitness, vitamin D levels and haemodynamic parameters in young Saudi females.

作者信息

Al Asoom Lubna I, Al Hariri Mohammad T

机构信息

Physiology Department, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, KSA.

出版信息

J Taibah Univ Med Sci. 2017 Jun 15;13(1):51-57. doi: 10.1016/j.jtumed.2017.05.004. eCollection 2018 Feb.

Abstract

OBJECTIVES

In this study, we assessed the possible association of adiposity, physical fitness, vitamin D levels and haemodynamic parameters as intermediate risk factors for cardiovascular health in young Saudi women.

METHODS

A total of 87 young healthy Saudi women were recruited in this cross-sectional study during 2014-2015. The body weight, height, waist and hip circumference, and plasma 25-hydroxyvitamin D (25[OH] D) levels were measured. The exercise stress test was performed to determine the pulse rate, blood pressure (BP), ECG, and VO. Multiple linear regression models were generated for the resting (r) and maximum (m) diastolic (D) and systolic (s) arterial BP and pulse rate (PR), adiposity markers, VO, and plasma levels of 25(OH) D.

RESULTS

A multiple linear regression model was significant for the rDBP, mDBP, rSBP, and mSBP with adjusted R (6.5, 10.2, 8.3, and 4.5%, respectively). Except for VO in the mDBP model, none of the included risk factors were significant according to the t-test.

CONCLUSION

This study showed the association of high adiposity and decreased physical fitness with haemodynamic parameters in young Saudi women. An exaggerated exercise DBP might predict future cardiovascular risk in unfit young women.

摘要

目的

在本研究中,我们评估了肥胖、体能、维生素D水平和血流动力学参数作为沙特年轻女性心血管健康中间危险因素的可能关联。

方法

在2014年至2015年期间,共有87名年轻健康的沙特女性被纳入这项横断面研究。测量了体重、身高、腰围和臀围以及血浆25-羟基维生素D(25[OH]D)水平。进行运动应激试验以确定脉搏率、血压(BP)、心电图和VO。针对静息(r)和最大(m)舒张压(D)和收缩压(s)动脉血压以及脉搏率(PR)、肥胖标志物、VO和25(OH)D血浆水平生成了多个线性回归模型。

结果

一个多元线性回归模型对rDBP、mDBP、rSBP和mSBP具有显著性,调整后的R分别为6.5%、10.2%、8.3%和4.5%。根据t检验,除了mDBP模型中的VO外,所纳入的危险因素均无显著性。

结论

本研究表明沙特年轻女性中肥胖程度高和体能下降与血流动力学参数有关。运动时舒张压过高可能预示着身体不健康的年轻女性未来的心血管风险。

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本文引用的文献

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J Hypertens. 2016 Sep;34(9):1796-803. doi: 10.1097/HJH.0000000000000996.
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Obesity and public health in the Kingdom of Saudi Arabia.沙特阿拉伯王国的肥胖与公共卫生
Rev Environ Health. 2015;30(3):191-205. doi: 10.1515/reveh-2015-0008.
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Low vitamin D is associated with hypertension in paediatric obesity.维生素D水平低与儿童肥胖中的高血压有关。
J Paediatr Child Health. 2015 Dec;51(12):1207-13. doi: 10.1111/jpc.12935. Epub 2015 Jun 8.
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Vitamin D deficiency independent of hypocalcemia elevates blood pressure in rats.
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