Najjar Ahmed A, Rasheedi Jameel K, Kurdi Khalil I, Hasan Ahmed A, Almekhlafi Mohammed A, Baeesa Saleh S
Division of Neurosurgery, Faculty of Medicine, King Abdulaziz University, Jeddah, KSA.
Division of Neurology, Faculty of Medicine, King Abdulaziz University, Jeddah, KSA.
J Taibah Univ Med Sci. 2017 Jul 21;13(1):87-92. doi: 10.1016/j.jtumed.2017.06.004. eCollection 2018 Feb.
Cerebral venous sinus thrombosis (CVST) is a severe clinical condition that manifests with diverse symptoms that can be mild, taking the form of a headache, or can be life-threatening, with raised intracranial pressure and herniation. Despite systemic anticoagulation treatment, CVST still carries a mortality risk of approximately 10% because of the failure of venous recanalization by anticoagulants alone. This paper describes two cases with extensive CVST who presented with progressive neurological deterioration despite adequate systemic anticoagulation treatment. Both patients were successfully treated with endovascular clot removal using suction thrombectomy techniques with immediate recanalization of the sinuses and rapid radiographic improvement. The described therapy appears effective and safe; however, further studies are needed to validate the effectiveness of this treatment.
脑静脉窦血栓形成(CVST)是一种严重的临床病症,其症状多样,可表现为轻微的头痛,也可能危及生命,出现颅内压升高和脑疝。尽管采用了全身抗凝治疗,但由于仅靠抗凝剂无法使静脉再通,CVST的死亡率仍约为10%。本文描述了两例广泛CVST患者,尽管进行了充分的全身抗凝治疗,仍出现进行性神经功能恶化。两名患者均通过使用抽吸血栓切除术技术进行血管内血栓清除成功治疗,窦道立即再通,影像学迅速改善。所述治疗方法似乎有效且安全;然而,需要进一步研究来验证这种治疗的有效性。