MMWR Morb Mortal Wkly Rep. 2019 Aug 23;68(33):713-717. doi: 10.15585/mmwr.mm6833a1.
In September 2018, CDC identified Salmonella enterica serotype Newport (Newport) infections that were multidrug resistant (MDR), with decreased susceptibility to azithromycin, a recommended oral treatment agent. Until 2017, decreased susceptibility to azithromycin had occurred in fewer than 0.5% of Salmonella isolates from U.S. residents. This report summarizes the investigation of a multistate MDR Salmonella outbreak conducted by CDC, state and local health departments, and the U.S. Department of Agriculture's Food Safety and Inspection Service. During June 2018-March 2019, 255 cases of infection with the outbreak strain were identified in 32 states; 43% of patients (89 of 206 with information on travel) reported recent travel to Mexico. Infections were linked to consumption of soft cheese obtained in Mexico and beef obtained in the United States. Consumers should avoid eating soft cheese that could be made from unpasteurized milk, regardless of the source of the cheese. When preparing beef, a food thermometer should be used to ensure that appropriate cooking temperatures are reached. When antibiotic treatment is needed for a patient, clinicians should choose antibiotics based on susceptibility testing wherever possible.
2018 年 9 月，美国疾病控制与预防中心（CDC）鉴定出了对多种药物具有耐药性（MDR）的肠炎沙门氏菌血清型纽波特（Newport）感染，对阿奇霉素的敏感性降低，阿奇霉素是一种推荐的口服治疗药物。直到 2017 年，美国居民分离出的沙门氏菌对阿奇霉素的敏感性降低发生率还不到 0.5%。本报告总结了由美国疾病控制与预防中心、州和地方卫生部门以及美国农业部食品安全检验局开展的一项多州耐药性沙门氏菌爆发调查。2018 年 6 月至 2019 年 3 月期间，在 32 个州共发现了 255 例感染该疫情菌株的病例；43%的患者（206 例中有信息可查的 89 例）报告了近期前往墨西哥的旅行。感染与食用在墨西哥获得的软奶酪和在美国获得的牛肉有关。消费者应避免食用可能由未经巴氏消毒的牛奶制成的软奶酪，无论奶酪的来源如何。在准备牛肉时，应使用食品温度计确保达到适当的烹饪温度。当患者需要抗生素治疗时，临床医生应尽可能根据药敏试验选择抗生素。
