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未从事多氯联苯职业暴露的女性母乳中的多氯联苯残留

Residues of polychlorinated biphenyls in breast milk of women non-occupationally exposed to PCBs.

作者信息

Hrubá D, Dubský H, Totusek J, Koukalová H

机构信息

Department of Hygiene and Epidemiology, Medical Faculty, J. E. Purkynĕ University, Brno, Czechoslovakia.

出版信息

J Hyg Epidemiol Microbiol Immunol. 1988;32(3):273-8.

PMID:3143758
Abstract

Samples of breast milk were collected from 27 women and examined for residues of polychlorinated biphenyls (PCBs) using gas-liquid chromatography. A questionnaire was used to obtain information on environmental factors relevant to the women's exposure to PCBs. The levels of breast milk PCB residues were considered in relation to the women's medical history before and during pregnancy and to the health status of the infants. Despite the fact that the production and use of PCBs were banned in Czechoslovakia in 1982, all breast milk samples tested had detectable levels of PCBs, with the average value of 2,411 ng.g-1 milk fat (i.e., 22.8 ng.g-1 whole milk). In 25% of the women the PCB levels were higher than 2,500 ng.g-1 milk fat, which is considered a limit concentration for PCB in breast milk.

摘要

从27名女性身上采集了母乳样本,并使用气液色谱法检测其中多氯联苯(PCBs)的残留量。通过问卷调查获取了与这些女性接触多氯联苯相关的环境因素信息。同时,还考虑了母乳中多氯联苯残留水平与这些女性怀孕前后的病史以及婴儿健康状况之间的关系。尽管捷克斯洛伐克在1982年就已禁止生产和使用多氯联苯,但所有检测的母乳样本中都能检测到多氯联苯,其平均含量为2411纳克/克乳脂肪(即22.8纳克/克全脂牛奶)。25%的女性母乳中多氯联苯含量高于2500纳克/克乳脂肪,这一含量被视为母乳中多氯联苯的极限浓度。

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