Bahar Moni Ahmed Suparno, Hoque Monirul, Mollah Rayhan Ali, Ivy Razia Sultana, Mujib Israt
Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang and WIDAD University College, Kuantan, Malaysia.
Ibrahim Medical College and BIRDEM General Hospital, Dhaka, Bangladesh.
J Hand Surg Asian Pac Vol. 2019 Sep;24(3):317-322. doi: 10.1142/S2424835519500401.
Hand infection in diabetics is an often ignored but challenging condition. If not addressed effectively, it may result in long term disability, contracture, amputation and even death. From August 2014 to December 2015, a study was done in our centre, where 49 diabetic hand infection cases were analyzed in two groups, superficial and deep hand infection. Mean age of the patients was 51.63 years. There were 21 superficial infections and 28 deep infections. Cause of infection was unknown or spontaneous in 16 cases, traumatic laceration or crush in 14 patients, following minor prick in 10 cases. Most of the cases were the results of neglected minor wound. Forty-one patients were insulin dependent. Five cases were diagnosed as diabetic at the time of treatment. Four patients were treated conservatively and 45 (92%) cases required operation in the form of incision, drainage and debridement. In 16 (35%) cases, wound was left open and was healed by secondary intention following regular dressing. In five patients, wound was closed secondarily. Partial thickness skin graft was applied in 15 cases. Seven patients were treated with flap coverage. Partial digital or ray amputation were done in 16 cases. All fingers except thumb were amputated in one case and amputation from wrist was done in another patient. Wound swabs were taken, and antibiotics were changed or continued accordingly. But reports of 26 cases were available. No growth was found in four cases, monomicrobial infection was found in 15 patients and polymicrobial in seven cases. Infection resolved with healing in 47 cases. Two patients died during treatment from sepsis, both were insulin dependent, had associated renal failure and from deep infection group. One patient developed severe mental disorder. For diabetic hand infection, early diagnosis and prompt treatment with appropriate antibiotics and emergency surgery with extensile incision is crucial. Primary amputation of the part could be life and limb saving.
糖尿病患者的手部感染是一种常被忽视但颇具挑战性的病症。若未得到有效治疗,可能导致长期残疾、挛缩、截肢甚至死亡。2014年8月至2015年12月,我们中心开展了一项研究,对49例糖尿病手部感染病例进行了分组分析,分为手部浅部感染和深部感染。患者的平均年龄为51.63岁。其中浅部感染21例,深部感染28例。16例感染原因不明或为自发性感染,14例因创伤性撕裂或挤压伤,10例因轻微刺伤。大多数病例是因忽视小伤口所致。41例患者依赖胰岛素治疗。5例在治疗时被诊断为糖尿病。4例患者接受保守治疗,45例(92%)患者需要进行切开、引流和清创等手术治疗。16例(35%)患者伤口敞开,经定期换药后二期愈合。5例患者伤口二期缝合。15例患者进行了部分厚度皮肤移植。7例患者采用皮瓣覆盖治疗。16例患者进行了部分手指或指骨截肢。1例患者除拇指外所有手指均被截肢,另1例患者进行了腕部截肢。采集伤口拭子,并据此更换或继续使用抗生素。但仅获得了26例患者的报告。4例未发现细菌生长,15例为单一微生物感染,7例为多种微生物感染。47例患者感染消退且伤口愈合。2例患者在治疗期间因败血症死亡,均依赖胰岛素治疗,伴有肾衰竭,且来自深部感染组。1例患者出现严重精神障碍。对于糖尿病手部感染,早期诊断并及时使用适当抗生素进行治疗,以及采用扩展性切开的急诊手术至关重要。对病变部位进行一期截肢可能挽救生命和肢体。