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The Other Side of the Coin: Nocebo Effects and Psychotherapy.硬币的另一面:反安慰剂效应与心理治疗。
Front Psychiatry. 2019 Aug 8;10:555. doi: 10.3389/fpsyt.2019.00555. eCollection 2019.
2
[Placebo and nocebo : How can they be used or avoided?].[安慰剂与反安慰剂:如何使用或避免它们?]
Internist (Berl). 2017 Oct;58(10):1102-1110. doi: 10.1007/s00108-017-0294-0.
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Pain Modulation: From Conditioned Pain Modulation to Placebo and Nocebo Effects in Experimental and Clinical Pain.疼痛调制:从条件性疼痛调制到实验和临床疼痛中的安慰剂和反安慰剂效应。
Int Rev Neurobiol. 2018;139:255-296. doi: 10.1016/bs.irn.2018.07.024. Epub 2018 Aug 14.
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Medical practice and placebo response: an inseparable bond?医学实践与安慰剂效应:不可分割的联系?
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[Nocebo--the antipode to placebo].[反安慰剂效应——安慰剂的对立面]
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[Nocebo--the opposite of placebo].[反安慰剂效应——安慰剂的对立面]
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The Placebo and Nocebo Phenomena: Their Clinical Management and Impact on Treatment Outcomes.安慰剂和反安慰剂现象:它们的临床管理及其对治疗结果的影响。
Clin Ther. 2017 Mar;39(3):477-486. doi: 10.1016/j.clinthera.2017.01.031. Epub 2017 Feb 23.
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Physicians' beliefs about placebo and nocebo effects in antidepressants - an online survey among German practitioners.医生对抗抑郁药中安慰剂和反安慰剂效应的看法——一项针对德国从业者的在线调查
PLoS One. 2017 May 31;12(5):e0178719. doi: 10.1371/journal.pone.0178719. eCollection 2017.
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Nocebo expectations rather than placebo expectations affect topical pain relief: A randomized clinical trial.负面预期而非正面预期影响局部止痛效果:一项随机临床试验。
Biomed Pharmacother. 2024 Jun;175:116728. doi: 10.1016/j.biopha.2024.116728. Epub 2024 May 10.

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Placebo, Nocebo, and Machine Learning: How Generative AI Could Shape Patient Perception in Mental Health Care.安慰剂、反安慰剂与机器学习:生成式人工智能如何塑造精神卫生保健中的患者认知。
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Eye movement desensitization and reprocessing (EMDR) therapy or supportive counseling prior to exposure therapy in patients with panic disorder: study protocol for a multicenter randomized controlled trial (IMPROVE).眼动脱敏再处理(EMDR)疗法或支持性咨询在惊恐障碍患者暴露疗法之前的应用:一项多中心随机对照试验(IMPROVE)的研究方案。
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Chronic pain concepts of pediatricians: a qualitative survey.儿科医生的慢性疼痛观念:一项定性调查。
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Fear of Covid-19: Insights from Evolutionary Behavioral Science.对新冠病毒的恐惧:来自进化行为科学的见解
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What are the Key Characteristics of a 'Good' Psychotherapy? Calling for Ethical Patient Involvement.“好的”心理治疗的关键特征是什么?呼吁患者进行符合伦理的参与。
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本文引用的文献

1
Psychotherapy: A World of Meanings.心理治疗:一个充满意义的世界。
Front Psychol. 2019 Mar 22;10:460. doi: 10.3389/fpsyg.2019.00460. eCollection 2019.
2
Effects and Components of Placebos with a Psychological Treatment Rationale - Three Randomized-Controlled Studies.安慰剂效应及其与心理治疗原理的关系——三项随机对照研究。
Sci Rep. 2019 Feb 5;9(1):1421. doi: 10.1038/s41598-018-37945-1.
3
When a Placebo Is Not a Placebo: Problems and Solutions to the Gold Standard in Psychotherapy Research.当安慰剂并非安慰剂时:心理治疗研究金标准中的问题与解决方案。
Front Psychol. 2018 Nov 26;9:2317. doi: 10.3389/fpsyg.2018.02317. eCollection 2018.
4
Psychotherapy and Placebos: Manifesto for Conceptual Clarity.心理治疗与安慰剂:概念清晰宣言。
Front Psychiatry. 2018 Aug 20;9:379. doi: 10.3389/fpsyt.2018.00379. eCollection 2018.
5
How to address the placebo response in the prescription SSRIs and SNRIs in children and adolescents.如何解决儿童和青少年处方 SSRIs 和 SNRIs 中的安慰剂反应。
Expert Opin Drug Saf. 2018 Jun;17(6):537-540. doi: 10.1080/14740338.2018.1475558. Epub 2018 May 21.
6
The Underestimated Significance of Conditioning in Placebo Hypoalgesia and Nocebo Hyperalgesia.条件作用在安慰剂性痛觉减退和反安慰剂性痛觉过敏中被低估的重要性。
Pain Res Manag. 2018 Jan 28;2018:6841985. doi: 10.1155/2018/6841985. eCollection 2018.
7
Beware of Nocebo-Paternalism: Pitfalls of Tailored Nondisclosure.谨防反安慰剂家长作风:针对性信息隐瞒的陷阱。
Am J Bioeth. 2017 Jun;17(6):56-58. doi: 10.1080/15265161.2017.1314049.
8
Tell Me the Truth and I Will Not Be Harmed: Informed Consents and Nocebo Effects.告诉我真相,我就不会受到伤害:知情同意与反安慰剂效应。
Am J Bioeth. 2017 Jun;17(6):46-48. doi: 10.1080/15265161.2017.1314057.
9
Preventing Nocebo Effects of Informed Consent Without Paternalism.在不采取家长式作风的情况下防止知情同意中的反安慰剂效应。
Am J Bioeth. 2017 Jun;17(6):44-46. doi: 10.1080/15265161.2017.1314056.
10
Harnessing the placebo effect: Exploring the influence of physician characteristics on placebo response.利用安慰剂效应:探究医生特征对安慰剂反应的影响。
Health Psychol. 2017 Nov;36(11):1074-1082. doi: 10.1037/hea0000499. Epub 2017 Mar 9.

硬币的另一面:反安慰剂效应与心理治疗。

The Other Side of the Coin: Nocebo Effects and Psychotherapy.

作者信息

Locher Cosima, Koechlin Helen, Gaab Jens, Gerger Heike

机构信息

Division of Clinical Psychology and Psychotherapy, Faculty of Psychology, University of Basel, Basel, Switzerland.

School of Psychology, University of Plymounth, Plymouth, United Kingdom.

出版信息

Front Psychiatry. 2019 Aug 8;10:555. doi: 10.3389/fpsyt.2019.00555. eCollection 2019.

DOI:10.3389/fpsyt.2019.00555
PMID:31440174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6694178/
Abstract

Psychotherapy and placebo have a long history, and both have been shown to have significant and clinically meaningful effects. In the last 100 years and up to today, psychotherapy has been subject to an enduring and often heated debate about its mechanisms and its possible relationship to placebos and their effects. However, there is little awareness of the placebo effects' counterpart-nocebo effects (from Latin "I will harm")-in the context of psychotherapy. Embedded in the controversy of whether psychotherapy and placebo share some unwanted proximity in terms of effects and mechanisms, the question arises which role nocebo effects may play in relation to psychotherapy. By using two examples, this article analyzes and discusses two different kinds of possible associations between psychotherapy and nocebo effects. We close with possibilities of how to prevent the occurrence of nocebo effects in psychotherapy, including some specific recommendations for clinical practice.

摘要

心理治疗和安慰剂有着悠久的历史,并且两者都已被证明具有显著且具有临床意义的效果。在过去的100年直至今日,心理治疗一直处于关于其机制以及它与安慰剂及其效果可能存在的关系的持久且常常激烈的争论之中。然而,在心理治疗的背景下,人们对安慰剂效应的对应面——反安慰剂效应(源自拉丁语“我将伤害”)却知之甚少。在心理治疗和安慰剂在效果及机制方面是否存在一些不必要的相似性这一争议中,出现了反安慰剂效应在心理治疗中可能扮演何种角色的问题。通过两个例子,本文分析并讨论了心理治疗与反安慰剂效应之间两种不同类型的可能关联。我们以如何预防心理治疗中反安慰剂效应的发生的可能性作为结尾,包括一些针对临床实践的具体建议。