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镉对早期发育虹鳟鱼(Oncorhynchus mykiss)的毒理学潜力。

Toxicological Potential of Cadmium Impact on Rainbow Trout (Oncorhynchus mykiss) in Early Development.

机构信息

Nature Research Centre, Akademijos St. 2, 08412, Vilnius, Lithuania.

Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko St. 24, 03225, Vilnius, Lithuania.

出版信息

Bull Environ Contam Toxicol. 2019 Oct;103(4):544-550. doi: 10.1007/s00128-019-02694-y. Epub 2019 Aug 22.

Abstract

Cadmium (Cd) is a toxic element widely distributed in the aquatic environment and producing a wide variety of harmful effects. In this study, the acute toxicity (96 h LC50) of Cd to rainbow trout Oncorhynchus mykiss embryos and larvae was determined. The obtained results showed that hatched larvae were the most sensitive to Cd exposure. After 4 days of exposure, embryos were found to have accumulated greater concentrations of Cd than larvae. Exposure to Cd at sublethal concentrations produced deleterious, exposure duration-related effects on biological parameters (mortality, heart rate and gill ventilation frequency) of larvae. Cd induced a significant elevation of all the studied geno- and cytotoxicity endpoints in larval erythroblasts.

摘要

镉(Cd)是一种广泛分布于水生态环境中的有毒元素,会产生多种有害影响。本研究测定了镉对虹鳟鱼胚胎和幼鱼的急性毒性(96 h LC50)。结果表明,孵化后的幼鱼对镉暴露最为敏感。暴露 4 天后,胚胎中积累的镉浓度大于幼鱼。亚致死浓度的镉暴露对幼鱼的生物参数(死亡率、心率和鳃通气频率)产生了有害的、与暴露时间相关的影响。镉诱导幼鱼红细胞中所有研究的遗传毒性和细胞毒性指标显著升高。

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