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牙本质弹性性质的多尺度细观力学建模。

Multiscale micromechanical modeling of the elastic properties of dentin.

机构信息

Department of Mechanical and Aerospace Engineering, New Mexico State University. Las Cruces, NM, 88003, USA.

Department of Mechanical and Aerospace Engineering, New Mexico State University. Las Cruces, NM, 88003, USA.

出版信息

J Mech Behav Biomed Mater. 2019 Dec;100:103397. doi: 10.1016/j.jmbbm.2019.103397. Epub 2019 Aug 14.

DOI:10.1016/j.jmbbm.2019.103397
PMID:31442944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8049631/
Abstract

The paper focuses on multiscale modeling of the elastic properties of dentin. It is modeled as a hierarchical structure consisting of collagen fibers and hydroxyapatite particles at the lower level. Different concentrations of hydroxyapatite in this tissue correspond to peritubular and intertubular dentins. Then, the overall material is modeled as intertubular dentin matrix containing parallel cylindrical holes (the tubules) surrounded by layers of peritubular dentin. At each microstructural level, the model accounts for anisotropy of the constituents. The model predictions are compared with experimental data available in literature.

摘要

本文侧重于牙本质弹性性质的多尺度建模。它被建模为一种分层结构,由较低层次的胶原纤维和羟磷灰石颗粒组成。该组织中不同浓度的羟磷灰石对应于管周和管间牙本质。然后,整体材料被建模为包含平行圆柱孔(管)的管间牙本质基质,这些孔被管周牙本质层包围。在每个微观结构水平上,该模型考虑了组成物的各向异性。模型预测与文献中可用的实验数据进行了比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/020a7758102b/nihms-1538164-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/c4eafab82c66/nihms-1538164-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/60e2570c9df0/nihms-1538164-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/7c8e328d6aa5/nihms-1538164-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/c121b3d51fde/nihms-1538164-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/9cb553808123/nihms-1538164-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/020a7758102b/nihms-1538164-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/c4eafab82c66/nihms-1538164-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/60e2570c9df0/nihms-1538164-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/7c8e328d6aa5/nihms-1538164-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/c121b3d51fde/nihms-1538164-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/9cb553808123/nihms-1538164-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c98/8049631/020a7758102b/nihms-1538164-f0006.jpg

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本文引用的文献

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Energy dissipation in mammalian collagen fibrils: Cyclic strain-induced damping, toughening, and strengthening.哺乳动物胶原原纤维中的能量耗散:循环应变诱导的阻尼、增韧和增强。
Acta Biomater. 2018 Oct 15;80:217-227. doi: 10.1016/j.actbio.2018.09.027. Epub 2018 Sep 19.
2
Fraction-exponential representation of the viscoelastic properties of dentin.牙本质粘弹性特性的分数指数表示法。
Int J Eng Sci. 2017 Feb;111:52-60. doi: 10.1016/j.ijengsci.2016.11.005. Epub 2016 Nov 25.
3
The peritubular reinforcement effect of porous dentine microstructure.
多孔牙本质微结构的肾小管周围增强效应。
PLoS One. 2017 Aug 31;12(8):e0183982. doi: 10.1371/journal.pone.0183982. eCollection 2017.
4
Protein-free formation of bone-like apatite: New insights into the key role of carbonation.无蛋白条件下类骨磷灰石的形成:对碳酸化关键作用的新见解。
Biomaterials. 2017 May;127:75-88. doi: 10.1016/j.biomaterials.2017.02.029. Epub 2017 Feb 27.
5
Micro-mechanical properties of the tendon-to-bone attachment.肌腱与骨附着处的微观力学特性。
Acta Biomater. 2017 Jul 1;56:25-35. doi: 10.1016/j.actbio.2017.01.037. Epub 2017 Jan 11.
6
Effect of aging on the microstructure, hardness and chemical composition of dentin.衰老对牙本质微观结构、硬度及化学成分的影响。
Arch Oral Biol. 2015 Dec;60(12):1811-20. doi: 10.1016/j.archoralbio.2015.10.002. Epub 2015 Oct 9.
7
Multiscale modelling and diffraction-based characterization of elastic behaviour of human dentine.多尺度建模与基于衍射的人牙本质弹性行为表征。
Acta Biomater. 2013 Aug;9(8):7937-47. doi: 10.1016/j.actbio.2013.04.020. Epub 2013 Apr 18.
8
Enamel and dentin as multi-scale bio-composites.牙釉质和牙本质作为多尺度生物复合材料。
J Mech Behav Biomed Mater. 2012 Aug;12:174-83. doi: 10.1016/j.jmbbm.2012.03.007. Epub 2012 Jun 9.
9
The dentin organic matrix - limitations of restorative dentistry hidden on the nanometer scale.牙本质有机基质——纳米尺度下隐藏的修复牙科局限性。
Acta Biomater. 2012 Jul;8(7):2419-33. doi: 10.1016/j.actbio.2012.02.022. Epub 2012 Mar 10.
10
Chemical composition and structure of peritubular and intertubular human dentine revisited.重新探讨人牙本质小管周和小管间的化学成分和结构。
Arch Oral Biol. 2012 Apr;57(4):383-91. doi: 10.1016/j.archoralbio.2011.09.008. Epub 2011 Oct 11.