Is there a genetic factor in flecainide toxicity?
作者信息
Beckmann J, Hertrampf R, Gundert-Remy U, Mikus G, Gross A S, Eichelbaum M
机构信息
Abteilung für Experimentelle und Klinische Pharmakologie, Bundesgesundheitsamt, Berlin, Federal Republic of Germany.
出版信息
BMJ. 1988 Nov 19;297(6659):1316. doi: 10.1136/bmj.297.6659.1316.
Abstract
摘要
相似文献
1
Is there a genetic factor in flecainide toxicity?氟卡尼毒性是否存在遗传因素？
BMJ. 1988 Nov 19;297(6659):1316. doi: 10.1136/bmj.297.6659.1316.
2
Stereoselective disposition of flecainide in relation to the sparteine/debrisoquine metaboliser phenotype.氟卡尼相对于司巴丁/异喹胍代谢表型的立体选择性分布。
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3
The influence of the sparteine/debrisoquin phenotype on the disposition of flecainide.司巴丁/异喹胍代谢表型对氟卡尼处置的影响。
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4
Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH.在尿流和pH值未得到控制的情况下多形性氟卡尼的处置情况
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5
Transient giant inverted T waves during flecainide intoxication.氟卡尼中毒时的短暂性巨大倒置T波。
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6
Flecainide half-life prolongation in 2 patients with congestive heart failure and complex ventricular arrhythmias.2例充血性心力衰竭合并复杂性室性心律失常患者的氟卡尼半衰期延长。
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[Flecainide. A new anti-arrhythmic agent].[氟卡尼。一种新型抗心律失常药物]
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Flecainide acetate: critical care administration guidelines.醋酸氟卡尼：重症监护用药指南。
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Hair analysis of flecainide for assessing the individual drug-taking behavior.分析头发中的氟卡尼以评估个体用药行为。
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Case Files from the University of California San Diego Medical Toxicology Fellowship: Neonatal Flecainide Toxicity from an Accidental Dosing Error.加利福尼亚大学圣地亚哥分校医学毒理学奖学金项目病例档案：因意外用药剂量错误导致的新生儿氟卡尼中毒
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Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target.THN102（莫达非尼与氟卡尼的组合）对健康受试者40小时完全睡眠剥夺期间警觉性和认知的疗效：胶质连接蛋白作为治疗靶点
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Acquired long QT syndrome and ventricular tachycardia in a patient on flecainide therapy.接受氟卡尼治疗的患者发生获得性长QT综合征和室性心动过速。
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Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing.药物诱导的尖端扭转型室性心动过速的药物遗传学方面：改善临床药物开发和处方的潜在工具。
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Adverse effects of class I antiarrhythmic drugs.I类抗心律失常药物的不良反应。
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Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions.利用体外和体内数据评估代谢性药代动力学相互作用的可能性。
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Clinical significance of genetic influences on cardiovascular drug metabolism.基因对心血管药物代谢影响的临床意义。
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Estimation of the absolute bioavailability of flecainide using stable isotope technique.使用稳定同位素技术估算氟卡尼的绝对生物利用度。
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9
Clinical significance of the sparteine/debrisoquine oxidation polymorphism.司巴丁/异喹胍氧化多态性的临床意义
Eur J Clin Pharmacol. 1989;36(6):537-47. doi: 10.1007/BF00637732.
10
Stereoselective disposition of flecainide in relation to the sparteine/debrisoquine metaboliser phenotype.氟卡尼相对于司巴丁/异喹胍代谢表型的立体选择性分布。
Br J Clin Pharmacol. 1989 Nov;28(5):555-66. doi: 10.1111/j.1365-2125.1989.tb03542.x.
本文引用的文献
1
Oral flecainide acetate for the treatment of ventricular arrhythmias.口服醋酸氟卡尼治疗室性心律失常。
N Engl J Med. 1981 Aug 27;305(9):473-7. doi: 10.1056/NEJM198108273050901.
2
Polymorphic drug oxidation in humans.人类的多态性药物氧化
Fed Proc. 1984 May 15;43(8):2298-302.
3
Pharmacodynamics and side effects of flecainide acetate.
Clin Pharmacol Ther. 1986 Jul;40(1):101-7. doi: 10.1038/clpt.1986.145.
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