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虚假生命体征:疼痛程度不能预测出院时阿片类药物处方。

The false vital sign: When pain levels are not predictive of discharge opioid prescriptions.

机构信息

University of Kansas Medical Center, Departments of Otolaryngology-Head and Neck Surgery and Clinical Informatics, 3901 Rainbow Blvd, Mailstop 3010, Kansas City, KS 66160, United States.

University of Kansas Medical Center, Departments of Otolaryngology-Head and Neck Surgery and Clinical Informatics, 3901 Rainbow Blvd, Mailstop 3010, Kansas City, KS 66160, United States.

出版信息

Int J Med Inform. 2019 Sep;129:69-74. doi: 10.1016/j.ijmedinf.2019.05.005. Epub 2019 May 9.

Abstract

BACKGROUND

Pain gained recognition as a vital sign in the early 2000s, underscoring the importance of accurate documentation, characterization, and treatment of pain. No prior studies have demonstrated the utility of the 0-10 pain scale with respect to discharge opioid prescriptions, nor characterized the most influential factors in discharge prescriptions.

METHODS

Inpatient and emergency department(ED) encounters from July 1, 2012 to April 1, 2018 resulting in a discharge prescription for tablet opioid medications were identified. The primary outcome was to determine if pain levels in 24 h prior to discharge correlated with opioids (in milligrams of morphine equivalents (MME)) prescribed. Secondary outcomes included the impact of patient and prescriber demographics, demographics. A generalized linear model was created to investigate factors affecting the quantity of prescribed opioids.

RESULTS

n = 78,691 patient encounters. Overall mean adjusted MME for non-ED visits was 378 versus 197 for ED visits. Whites received the highest quantities; those identifying as non-white and non-black received the lowest. Women received significantly fewer discharge MMEs in both the ED and inpatient cohorts. Provider prescribing patterns exhibited the most profound effect on discharge MMEs. The most prolific (≥300 prescriptions over the study period) writing the largest amount. In the ED, there was a significant negative correlation between documented pain levels and discharge MMEs(ρ = 0.074,p < 0.001).

CONCLUSIONS

Pain scale was significantly negatively correlated with discharge MMEs in the ED and positively correlated in the inpatient population. Individual prescriber characteristics were the more influential variable, with prolific high prescribers writing for the largest MME amounts. The inverse association of pain and MMEs at discharge in the ED, and the large effect pre-existing prescriber patterns exhibited, both improved methodology for assessing and appropriately treating pain, and effective prescriber-targeted interventions, must be a priority.

摘要

背景

疼痛在 21 世纪初被确认为生命体征之一,这突显了准确记录、描述和治疗疼痛的重要性。以前没有研究表明 0-10 疼痛量表在出院阿片类药物处方方面的实用性,也没有描述出院处方中最具影响力的因素。

方法

确定了 2012 年 7 月 1 日至 2018 年 4 月 1 日期间因出院处方服用片剂阿片类药物而住院和急诊(ED)就诊的患者。主要结果是确定出院前 24 小时的疼痛水平是否与开处的阿片类药物(以吗啡等效剂量(MME)表示)相关。次要结果包括患者和处方医生的人口统计学特征,以及处方医生的人口统计学特征。创建了一个广义线性模型来研究影响规定阿片类药物数量的因素。

结果

n=78691 例患者就诊。非 ED 就诊的总体平均调整后 MME 为 378,而 ED 就诊的平均调整后 MME 为 197。白人获得的剂量最高;非白人和非黑人的剂量最低。在 ED 和住院患者队列中,女性接受的出院 MME 明显少于男性。提供者的处方模式对出院 MME 有最深远的影响。在研究期间开处 300 次以上处方的医生开处的剂量最大。在 ED,记录的疼痛水平与出院 MME 呈显著负相关(ρ=0.074,p<0.001)。

结论

疼痛量表与 ED 患者的出院 MME 呈显著负相关,与住院患者的出院 MME 呈正相关。个体处方医生的特征是更具影响力的变量,开处剂量最大的医生是高处方量医生。ED 中疼痛与 MME 之间的反向关联以及现有处方模式的巨大影响都表明,必须优先考虑评估和适当治疗疼痛的方法学改进,以及针对处方医生的有效干预措施。

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