University of Jyväskylä, Faculty of Sport and Health Sciences, Finland; Assistive Technology Centre, Central Finland Health Care District, Jyväskylä, Finland.
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
J Affect Disord. 2019 Dec 1;259:150-153. doi: 10.1016/j.jad.2019.08.039. Epub 2019 Aug 19.
The study aim was to examine association between leisure time physical activity (LTPA) and psychiatric comorbidities among people with depression.
Total 447 patients aged 35 years and older suffering from depressive symptoms (DS) and who were confirmed depression positive participated this study. The study was conducted between 2008 and 2011 in municipalities within Central Finland Hospital District. DS were determined with Beck Depression Inventory (BDI-21) with cutoff score ≥10 and psychiatric diagnoses were confirmed by Mini-International Neuropsychiatric Interview (M.I.N.I.). LTPA, other diseases as well as use of antidepressant were captured by self-reported questionnaire. Participants also took part in physical examination. The associations between LTPA and psychiatric comorbidities were analyzed using generalized linear models.
LTPA level was not related to number of psychiatric comorbidities (after adjustment for age, gender, BMI, BDI and use of antidepressant p = 0.24) among depressed patients. The higher levels of LTPA were linearly associated with lower cardiovascular diseases (p = 0.036) and obesity (p = 0.006) as well as fewer DS (p < 0.001) among depressed patients.
Possibility of LTPA level overestimation and study results generalizability to younger persons.
According to this study, LTPA level is not associated with psychiatric comorbidities among depressed patients in Finnish adult population. However, our results showed that the higher the LTPA level was, the less the participants suffered from depressive symptoms. In addition, higher levels of physical activity were associated with fewer heart diseases and obesity outlining the importance of overall health-care and health promotion although other forms of treatment are also needed.
本研究旨在探讨休闲时间体力活动（LTPA）与抑郁症患者合并精神疾病之间的关系。
本研究共纳入 447 名年龄在 35 岁及以上、患有抑郁症状（DS）并确诊为抑郁症的患者。该研究于 2008 年至 2011 年在芬兰中芬兰地区医院进行。DS 通过贝克抑郁量表（BDI-21）进行评估，截断值≥10 分，精神疾病诊断通过迷你国际神经精神访谈（MINI）确认。通过自我报告问卷收集 LTPA、其他疾病以及抗抑郁药物的使用情况。参与者还参加了体检。使用广义线性模型分析 LTPA 与精神共病之间的关系。
在调整年龄、性别、BMI、BDI 和抗抑郁药物使用情况后，LTPA 水平与抑郁患者的精神共病数量无关（p=0.24）。较高水平的 LTPA 与较低的心血管疾病（p=0.036）和肥胖（p=0.006）以及较少的 DS（p<0.001）呈线性相关。
可能存在 LTPA 水平高估以及研究结果在年轻人群中的推广性问题。
根据本研究，在芬兰成年人群中，LTPA 水平与抑郁患者的精神共病无关。然而，我们的结果表明，LTPA 水平越高，参与者患抑郁症状的可能性越低。此外，较高水平的体力活动与较少的心脏病和肥胖相关，这突出了整体健康护理和健康促进的重要性，尽管还需要其他形式的治疗。
