Office of Health Affairs, Ministry of Health, P.O. Box 393, PC 100, Muscat, Oman.
Virology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
J Infect Public Health. 2020 Feb;13(2):221-227. doi: 10.1016/j.jiph.2019.08.004. Epub 2019 Aug 21.
In 2016, the World Health Assembly adopted the hepatitis B (HB) elimination strategy that aims at ending HB by 2030. In this descriptive review we provide the progress made and challenges to achieving hepatitis B elimination by 2030 in Gulf Health Cooperated (GHC) states.
Data record from relevant online databases and reliable resources were reviewed until the end of 2017. The analysis was based on the core indicators of the WHO monitoring and evaluation framework for viral hepatitis B and the targets of the global health sector strategy by 2016‒2021.
The states introduced HB vaccination, including birth-dose for those under 5 years old, with global coverage of more than 95%, in order to prevent mother-to-child transmission of HBV. The prevalence of HB antigens declined in children under age 5 to less than 1%. However, the rate of vaccination among the most-at-risk populations remains suboptimal. All states have implemented safe blood transfusions and injection safety policies as well as universal laboratory-based surveillance for acute HB. However, surveillance for chronic HB and sequelae as well as estimation methods of morbidity and mortality to evaluate impact are not established. Similarly, harm reduction for people who inject drugs and testing and treatment policies and protocols for people with chronic HB are suboptimal.
Additional steps are required to strengthen immunisation among the most-at-risk populations, maintain high quality surveillance, use antiviral therapy to treat chronic HBV and stop unsafe injection practices for drug users. Establishing country-specific national hepatitis responses based on country priorities as well as the capacity of the home health sectors to address these needs are paramount. Achieving elimination targets will require a radical alteration in the current hepatitis response and this goal should be elevated to a higher priority in the public health arena.
2016 年,世界卫生大会通过了乙型肝炎(HB)消除战略,旨在 2030 年消除乙型肝炎。在本描述性综述中,我们提供了海湾合作委员会(GCC)国家在 2030 年之前实现乙型肝炎消除方面取得的进展和面临的挑战。
直到 2017 年底,审查了来自相关在线数据库和可靠资源的数据记录。该分析基于世界卫生组织监测和评价乙型肝炎框架的核心指标以及 2016-2021 年全球卫生部门战略的目标。
各国引入了乙型肝炎疫苗接种,包括为 5 岁以下儿童接种基础疫苗,全球覆盖率超过 95%,以防止乙型肝炎病毒母婴传播。5 岁以下儿童的乙型肝炎抗原流行率下降到不到 1%。然而,高危人群的疫苗接种率仍然不理想。所有国家都实施了安全输血和注射安全政策以及基于实验室的急性乙型肝炎监测。然而,尚未建立慢性乙型肝炎和后遗症监测以及发病率和死亡率评估方法来评价影响。同样,减少注射毒品者的危害以及为慢性乙型肝炎患者进行检测和治疗的政策和方案也不理想。
需要采取额外措施,加强高危人群的免疫接种,保持高质量监测,使用抗病毒疗法治疗慢性乙型肝炎,并停止注射毒品者不安全的注射行为。根据国家优先事项和国内卫生部门应对这些需求的能力,制定国家特定的国家肝炎应对计划至关重要。要实现消除目标,需要彻底改变当前的肝炎应对措施,将这一目标提升到公共卫生领域的更高优先级。