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[急性动脉闭塞的临床情况与治疗]

[Clinical aspects and treatment of acute arterial occlusion].

作者信息

Stirnemann P, Z'Brun A P, Mahler F

机构信息

Klinik für Thorax-, Herz- und Gefässchirurgie, Inselspital, Universität Bern.

出版信息

Schweiz Med Wochenschr. 1988 Nov 26;118(47):1767-72.

PMID:3144737
Abstract

163 patients underwent surgery for acute ischemia of the lower extremity between 1982 and 1986. Thrombosis was present in 50 cases and embolism in 113. Half of the patients with thrombosis showed signs of chronic occlusive disease of the arteries (intermittent claudication); in the latter group 2/3 of the patients had atrial fibrillation and 1/4 coronary heart disease. For embolism Fogarty-catheter clot extraction was performed, mainly under local anesthesia. This procedure is easy to perform even under emergency conditions (mortality 10%, amputation rate 8%). In contrast, the surgical procedure in thrombotic occlusion was more demanding (mortality 4%, amputation rate 16%) and in the case of severe ischemia had to be carried out on an emergency basis. In case of less severe ischemia the treatment consisted in initial heparinization and elective revascularization when the patient was stabilized. A new therapeutic approach involving local catheter thrombolysis, catheter clot aspiration and balloon dilatation is presented. The combined catheter intervention produces good results in 70% of patients, particularly those with femoral thrombosis.

摘要

1982年至1986年间,163例患者接受了下肢急性缺血手术。其中50例为血栓形成,113例为栓塞。一半血栓形成患者表现出慢性动脉闭塞性疾病的体征(间歇性跛行);在后一组中,2/3的患者患有心房颤动,1/4患有冠心病。对于栓塞,主要在局部麻醉下进行Fogarty导管取栓术。即使在紧急情况下,该手术也易于实施(死亡率10%,截肢率8%)。相比之下,血栓闭塞的手术操作要求更高(死亡率4%,截肢率16%),在严重缺血的情况下必须紧急进行。在缺血不太严重的情况下,治疗包括初始肝素化以及在患者病情稳定后进行选择性血管重建。本文介绍了一种新的治疗方法,包括局部导管溶栓、导管吸栓和球囊扩张。联合导管干预在70%的患者中取得了良好效果,尤其是股静脉血栓形成的患者。

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