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经桡动脉冠状动脉造影术中单导管与双导管策略的操作和临床性能:随机试验的荟萃分析。

Procedural and clinical performance of dual- versus single-catheter strategy for transradial coronary angiography: A meta-analysis of randomized trials.

机构信息

Department of Cardiology, University Heart Center Berlin and Charite University Medicine Berlin, Berlin, Germany.

German Centre for Cardiovascular Research (DZHK), Berlin, Germany.

出版信息

Catheter Cardiovasc Interv. 2020 Aug;96(2):276-282. doi: 10.1002/ccd.28458. Epub 2019 Aug 26.

DOI:10.1002/ccd.28458
PMID:31448867
Abstract

OBJECTIVES

We sought to compare the procedural and clinical performance of dual- versus single-catheter strategy for transradial coronary angiography.

BACKGROUND

The radial artery (RA) is recommended as the vascular access of choice in patients undergoing coronary angiography and intervention. The procedural and clinical performance of dual- versus single-catheter strategy in patients undergoing transradial coronary angiography remains a matter of debate.

METHODS

This is a study-level meta-analysis of randomized trials. The primary outcome was procedure time. The main secondary outcome was fluoroscopy time. Other outcomes of interest were contrast volume, crossover to other catheter strategy and RA spasm.

RESULTS

A total of 2,062 patients (978 randomly assigned to dual-catheter and 1,084 to single-catheter strategy) included in seven trials were available for the quantitative synthesis. A dual-catheter strategy was associated with procedure time (standardized mean difference [95% confidence intervals (CI)], 0.55 [-0.69, 1.78]; p = .32), fluoroscopy time (-0.36 [-2.39, 1.67]; p = .68) and contrast volume (-0.93 [-3.79, 1.94]; p = .44) comparable to a single-catheter strategy. The risk for crossover was lower (risk ratio [95% CI], 0.14 [0.03, 0.70]; p = .025) while the risk for RA spasm was higher (1.81 [1.54, 2.12]; p < .001) among patients assigned to dual- versus single-catheter strategy.

CONCLUSIONS

This meta-analysis provides evidence for a comparable procedural performance of either dual- or single-catheter strategy for transradial coronary angiography. The fewer crossovers with dual-catheter strategy occur at the expense of more frequent radial artery spasm.

摘要

目的

比较经桡动脉冠状动脉造影中双导管与单导管策略的手术和临床效果。

背景

桡动脉(RA)是行冠状动脉造影和介入治疗患者首选的血管入路。经桡动脉冠状动脉造影中双导管与单导管策略的手术和临床效果仍存在争议。

方法

这是一项随机试验的研究水平荟萃分析。主要结局是手术时间。主要次要结局是透视时间。其他感兴趣的结局是造影剂用量、交叉至其他导管策略和 RA 痉挛。

结果

共有 2062 例患者(978 例随机分配至双导管组,1084 例分配至单导管组)纳入 7 项试验进行定量合成。与单导管策略相比,双导管策略的手术时间(标准化均数差[95%置信区间(CI)],0.55[-0.69,1.78];p=0.32)、透视时间(-0.36[-2.39,1.67];p=0.68)和造影剂用量(-0.93[-3.79,1.94];p=0.44)相当。交叉风险较低(风险比[95%CI],0.14[0.03,0.70];p=0.025),而双导管组 RA 痉挛风险较高(1.81[1.54,2.12];p<0.001)。

结论

这项荟萃分析提供了证据,表明经桡动脉冠状动脉造影中双导管与单导管策略的手术效果相当。双导管策略的交叉较少,但其代价是更频繁的桡动脉痉挛。

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