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家庭访视在儿童和青少年 1 型糖尿病控制不佳中的应用

Home Visits for Children and Adolescents with Uncontrolled Type 1 Diabetes.

机构信息

Department of Pediatrics, University of California, Davis Health System, Sacramento, California.

Department of Public Health Sciences, University of California, Davis, Davis, California.

出版信息

Diabetes Technol Ther. 2020 Jan;22(1):34-41. doi: 10.1089/dia.2019.0214. Epub 2019 Sep 18.

Abstract

Home-based video visits were provided over one year as a supplement to in-person care for pediatric type 1 diabetes (T1D) patients with suboptimal glycemic control. We hypothesized that the intervention would be feasible and satisfactory for the target population and would significantly improve hemoglobin A1c (HbA1c) levels and completion of recommended quarterly diabetes clinic visits. This was a nonrandomized clinical trial. Fifty-seven patients aged 3-17 years with known T1D and HbA1c ≥8% (64 mmol/mol) were recruited to receive the intervention. The study population was 49% adolescent (13-17 years old) and 58% publicly insured patients. Video visits were scheduled every 4, 6, or 8 weeks depending on the HbA1c level. HbA1c levels as well as frequencies of clinic visits and of diabetes-related emergency department (ED) and hospital encounters were compared before and after the study. Thirty participants completed 12 months of video visits. The study cohort demonstrated significant improvement in mean HbA1c in both intention-to-treat ( = 57) analysis (10.8% [95 mmol/mol] to 10.0% [86 mmol/mol],  = 0.01) and per-protocol ( = 30) analysis (10.8% [95 mmol/mol] to 9.6% [81 mmol/mol],  = 0.004). Completion of ≥4 annual diabetes clinic visits improved significantly from 21% at baseline to 83% during the study period for the entire cohort,  < 0.0001. The frequency of diabetes-related ED and hospital encounters did not change significantly. Home-based video visits are a feasible supplement to in-person care for children and adolescents with T1D and suboptimal glycemic control and can successfully improve HbA1c levels and adherence to recommended frequency of care in this high-risk clinical population.

摘要

家庭视频访问作为对血糖控制不佳的儿童 1 型糖尿病(T1D)患者的门诊护理的补充,持续了一年。我们假设该干预措施对目标人群是可行且满意的,并且可以显著改善血红蛋白 A1c(HbA1c)水平和完成推荐的季度糖尿病诊所就诊次数。这是一项非随机临床试验。招募了 57 名年龄在 3-17 岁之间、已知患有 T1D 和 HbA1c≥8%(64mmol/mol)的患者接受该干预措施。研究人群中,青少年(13-17 岁)占 49%,公共保险患者占 58%。根据 HbA1c 水平,视频访问每 4、6 或 8 周安排一次。比较研究前后的 HbA1c 水平以及诊所就诊次数和糖尿病相关急诊室(ED)和医院就诊次数。30 名参与者完成了 12 个月的视频访问。意向治疗( = 57)分析显示,研究队列的平均 HbA1c 显著改善(10.8%[95mmol/mol]降至 10.0%[86mmol/mol], = 0.01),且符合方案( = 30)分析也显示出同样的结果(10.8%[95mmol/mol]降至 9.6%[81mmol/mol], = 0.004)。整个队列的所有患者的年度糖尿病诊所就诊次数从基线时的 21%显著增加到研究期间的 83%, < 0.0001。糖尿病相关 ED 和医院就诊次数没有显著变化。家庭视频访问是对血糖控制不佳的儿童和青少年 T1D 患者的门诊护理的可行补充,可成功改善 HbA1c 水平,并提高该高风险临床人群的推荐护理频率。

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